Reverse Transcriptase

Specialty Definitions: Reverse Transcriptase

Domain	Definitions
Medicine	An enzyme that can synthetize a single complementary strand of DNA from an mRNA sequence-the reverse of what normally happens in a cell. Source: European Union. (references)
Source: compiled by the editor from various references; see credits.

Top

Specialty Definition: Reverse transcriptase

(From Wikipedia, the free Encyclopedia)

Reverse transcriptase is an enzyme used by all retroviruses that transcribes the genetic information from the virus from RNA into DNA, which can integrate into the host genome. Usually, transcription only runs from DNA to RNA, catalyzed by RNA polymerase. An example of this kind of enzyme is the reverse transcriptase from the human immunodeficiency virus type 1 (PDB 1HMV, EC 2.7.7.49).

Reverse transcriptase is commonly used in the field of research to be able to apply the Polymerase chain reaction technique to RNA. The classical PCR technique can only be applied to DNA strands, but with the help of reverse transcriptase, RNA can be transcribed into DNA making PCR analysis of RNA molecules possible. The technique is collectively called: Reverse Transcriptase Polymerase Chain Reaction (RT-PCR).

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Reverse transcriptase."

Top

Crosswords: Reverse Transcriptase

English words defined with "reverse transcriptase": retrovirus. (references)

Specialty definitions using "reverse transcriptase": 1592, 1592U89 ♦ Abacavir, adefovir ♦ birg-587 ♦ cDNA, c-DNA, complementary DNA ♦ Delavirdine, DNA Footprinting ♦ efavirenz ♦ Gene Products, pol, Genes, pol, GW1592 ♦ HIV-1 Reverse Transcriptase ♦ Lamivudine, Long Interspersed Nucleotide Elements ♦ Nevirapine, non-nucleoside, non-nucleoside reverse transcriptase inhibitor ♦ oncornavirus, oncovirus ♦ Preveon ♦ reverse transcriptase inhibitor, Reverse Transcriptase Inhibitors, Reverse Transcriptase Polymerase Chain Reaction ♦ Stavudine, Sustiva ♦ Telomerase ♦ Viramune ♦ Zalcitabine, Ziagen. (references)

Top

Commercial Usage: Reverse Transcriptase

Domain	Title
Books	Structural-Aided Design of Antiviral Drugs: Application of the Method of Hiv-1 Protease and Siv Reverse Transcriptase (Comprehensive Summaries of upp (reference) (more book examples)
Source: compiled by the editor from various references; see credits.

Top

Photo Album: Reverse Transcriptase

Thumbnail	Description & Credit
	The human immunodeficiency virus (HIV-I) enters the T-lymphocyte where the virus loses its outer envelop, releasing its RNA and its reverse transcriptase. The reverse transcriptase builds a complimentary DNA strand from the viral RNA template. The DNA helix is inserted into the host genome. When this is transcribed by the infected cell, the new viral RNA and proteins are produced to form new viruses that then bud from the cell membrane, thus completing the life cycle of the virus. See artwork: GR-32.Credit: Trudy Nicholson (artist).
Source: compiled by the editor from various references; see credits.

Top

Non-Fiction Usage: Reverse Transcriptase

Subject	Topic	Quote
Health		Incidence is decreasing among HIV- infected patients as a result of new treatment modalities e.g., combination therapy with nucleoside reverse transcriptase inhibitors and protease inhibitors, as well as antimycobacterial prophylaxis. (references)
		Rabies RNA can be copied into a DNA molecule using reverse transcriptase (RT).� The DNA copy of rabies can then be amplified using polymerase chain reaction (PCR). This technique can confirm dFA results and can detect rabies virus in saliva and skin biopsy samples. (references)
Source: compiled by the editor from ICON Group International, Inc.; see credits.

Top

Expressions: Reverse Transcriptase

Expressions using "reverse transcriptase": HIV-1 Reverse Transcriptase ♦ reverse transcriptase inhibitor ♦ Reverse Transcriptase Inhibitors ♦ Reverse Transcriptase Polymerase Chain Reaction. Additional references.
Source: compiled by the editor from various references; see credits.

Top

Frequency of Internet Keywords: Reverse Transcriptase

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.

Expression	Frequency per Day
reverse transcriptase	20
reverse transcriptase inhibitor	6
reverse transcriptase pcr	3
nucleoside reverse transcriptase inhibitor	2
Source: compiled by the editor from various references; see credits.

Top

Modern Translations: Reverse Transcriptase

Language		Translations for "reverse transcriptase"; alternative meanings/domain in parentheses.
Danish		revers transcriptase (RNA-dependent DNA polymerase), omvendt transkriptase (RNA-dependent DNA polymerase). (various references)

Dutch		reverse transcriptase (RNA-dependent DNA polymerase). (various references)

Finnish		käänteiskopioijaentsyymi (RNA-dependent DNA polymerase). (various references)

French		transcriptase reverse, transcriptase inverse, ADN-polymérase ARN dépendante. (various references)

German		reverse Transkriptase (RNA-dependent DNA polymerase), Umkehrtranskriptase (RNA-dependent DNA polymerase). (various references)

Greek		ανάστροφη μεταγραφάση (RNA-dependent DNA polymerase), DΝΑ πολυμεράση εξαρτώμενη από το RΝΑ (RNA-dependent DNA polymerase). (various references)

Italian		trascrittasi inversa (RNA-dependent DNA polymerase). (various references)

Pig Latin		everseray anscriptasetray

Portuguese		transcriptase reversa (RNA-dependent DNA polymerase), polimerase do ADN dependente do ARN (RNA-dependent DNA polymerase). (various references)

Spanish		retrotranscriptasa (RNA-dependent DNA polymerase), transcriptasa inversa (RNA-dependent DNA polymerase), ADN polimerasa ARN dependiente (RNA-dependent DNA polymerase). (various references)

Swedish		reverse transcriptase (RNA-dependent DNA polymerase), omvänt transkriptas (RNA-dependent DNA polymerase). (various references)
Source: compiled by the editor from various translation references.

Top

Anagrams: Reverse Transcriptase

Scrabble® Enable2K-Verified Anagrams
	Words within the letters "a-a-c-e-e-e-e-i-n-p-r-r-r-r-s-s-s-t-t-v"
	-5 letters: pectinesterases, representatives.
Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.

Top