Copyright © Philip M. Parker, INSEAD. Terms of Use.
Definition: Zidovudine |
ZidovudineNoun1. An antiviral drug used in the treatment of AIDS; adverse side effects include liver damage and suppression of the bone marrow. Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved. |
| Domain | Definition |
Health | A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. (references) |
Source: compiled by the editor from various references; see credits. | |
Synonym: ZidovudineSynonym: azidothymidine (n). (additional references) |
| Domain | Title |
Books | |
Source: compiled by the editor from various references; see credits. | |
| Subject | Topic | Quote |
Health | Currently, the National Institutes of Health (NIH) is sponsoring two large, controlled trials of IVIG with and without zidovudine (AZT) in HIV-infected children. (references) | |
Source: compiled by the editor from ICON Group International, Inc.; see credits. | ||
| "Zidovudine" is generally used as a noun (singular) -- approximately 78.79% of the time. "Zidovudine" is used about 33 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted) |
| Parts of Speech | Percent | Usage per 100 Million Words | Rank in English |
| Noun (singular) | 78.79% | 26 | 68,323 |
| Noun (proper) | 18.18% | 6 | 143,867 |
| Lexical Verb (infinitive) | 3.03% | 1 | 339,140 |
| Total | 100.00% | 33 | N/A |
Source: compiled by the editor from several corpora; see credits.
| Hyphenated Usage | |
Beginning with "zidovudine": zidovudine-resistant. | |
| Source: compiled by the editor from various references; see credits. | |
| The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com. |
| Expression | Frequency per Day |
zidovudine | 14 |
| Source: compiled by the editor from various references; see credits. | |
| Language | Translations for "zidovudine"; alternative meanings/domain in parentheses. | ||||||||||||||||||||||
Danish | ziduvudin (azidotimidine, Retrovir), zidovudin, retrovir (azidotimidine, Retrovir). (various references) | ||||||||||||||||||||||
Dutch | zidovudine (azidotimidine, Retrovir), Retrovir (azidotimidine, Retrovir), AZT (azidothymidine, azidotimidine, Retrovir), azidothymidine (azidotimidine, Retrovir). (various references) | ||||||||||||||||||||||
Finnish | zidovudiini (azidotimidine, Retrovir), tsidovudiini (azidotimidine, Retrovir), AZT (azidotimidine, Retrovir), atsidotymidiini (azidotimidine, Retrovir). (various references) | ||||||||||||||||||||||
French | zidovudine, Retrovir, AZT, azidothymidine. (various references) | ||||||||||||||||||||||
German | Zidovudin (azidotimidine, Retrovir), Rotrovir (azidotimidine, Retrovir), AZT (Aschheim-Zondek test, azidotimidine, Retrovir). (various references) | ||||||||||||||||||||||
Greek | zidovudine (azidotimidine, Retrovir), retrovir (azidotimidine, Retrovir), ζιδοβουδίνη (azidotimidine, Retrovir), αζιδιοθυμιδίνη (azidotimidine, Retrovir), AZT (azidotimidine, Retrovir). (various references) | ||||||||||||||||||||||
Italian | zidovudina (azidotimidine, Retrovir), Retrovir (azidotimidine, Retrovir), AZT (azidotimidine, Retrovir), azidotimidina (azidotimidine, Retrovir). (various references) | ||||||||||||||||||||||
Pig Latin | idovudinezay zidovudina, azidotimidina (azidothymidine, azidotimidine, Retrovir). (various references) zidovudina, Retrovir (azidotimidine, Retrovir), cidovudina (azidotimidine, Retrovir), AZT (azidothymidine, azidotimidine, Retrovir), azidotimidina (azidothymidine, azidotimidine, Retrovir), 3'-azido-2',3'didexositimidina (azidotimidine, Retrovir). (various references) zidovudin (azidotimidine, Retrovir). (various references) | ||||||||||||||||||||||
Derivations | |
Words beginning with "zidovudine": zidovudines. (additional references) | |
| Source: compiled by the editor, based on several corpora (additional references). | |
Scrabble® Enable2K-Verified Anagrams | |
| Words within the letters "d-d-e-i-i-n-o-u-v-z" | |
-3 letters: divined, iodized, ionized. | |
-4 letters: devoid, divide, divine, indued, iodide, iodine, iodize, ionize, nevoid, voided. | |
-5 letters: devon, didie, dined, diode, dived, dizen, doven, dozed, dozen, envoi, indie, indue, iodid, iodin, ivied, nided, nudie, ovine, undid, video, vined, vodun, zoned. | |
| Words containing the letters "d-d-e-i-i-n-o-u-v-z" | |
+1 letter: zidovudines. | |
| Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro. | |
| 1. Definition 2. Synonyms 3. Usage: Commercial 4. Quotations: Non-fiction | 5. Usage Frequency 6. Expressions 7. Expressions: Internet 8. Translations: Modern | 9. Derivations 10. Anagrams 11. Bibliography |
Copyright © Philip M. Parker, INSEAD. Terms of Use.
