Ulcerative Colitis

Definition: Ulcerative Colitis

Ulcerative Colitis

Noun

1. A serious chronic inflammatory disease of the large intestine and rectum characterized by recurrent episodes of abdominal pain and fever and chills and profuse diarrhea.

Specialty Definition: Ulcerative Colitis

Domain	Definition
Health	Chronic inflammation of the colon that produces ulcers in its lining. This condition is marked by abdominal pain, cramps, and loose discharges of pus, blood, and mucus from the bowel. (references)
Source: compiled by the editor from various references; see credits.

Specialty Definition: Ulcerative colitis

Ulcerative colitis is an inflammatory disease of the bowel, that usually affects the distal end of the large intestine and rectum. It has no known cause, although there is a genetic component to susceptibility.

Ulcerative colitis is similar to Crohn's disease, but there are characteristic differences: ulcerative colitis is usually confined to the mucosa and submucosa, and affects whole areas of intestine. (Crohn's disease tends to be patchy, and affect more layers of intestine.)

Features

Chronic (> 6 months) of bloody diarrhea.
No infective cause of diarrhea found.
Inflammatory changes are mainly left sided or in the distal large bowel.
Disease variable in severity from patient to patient and time to time.
Significant risk of carcinoma after 10 years, which may in some cases require frequent surveillance biopsies or even prophylactic bowel removal.
Patients may have other auto-immune features.

Cause

The cause of ulcerative colitis is unknown, although infective agents have been suspected, and there is a genetic component to susceptibility.

Diagnosis

A long-standing history of bloody diarrhea, with no sign of infection, is consistent with ulcerative colitis. A biopsy can help confirm the diagnosis. Ulcerative colitis mainly affects the left side of the colon.

Course

People with ulcerative colitis will initially have bloody diarrhea (the severity of which is variable from time to time).

Because of destruction of the nerves in the bowel, movement may be impaired, and the intestine may dilate. This results in an extreme diarrheal disease, toxic megacolon.

Eventually the inflamed mucosa develops a risk of malignancy, requiring biopsy every few months. Sometimes the risk of malignancy is such that bowel resection is offered.

Treatment

Anti-diarrheal drugs should be avoided unless under specific doctors orders, as they can worsen the disease.

Anti-inflammatory drugs (such as Sulfasalazine) can be used, and in severe cases steroids may be given.

See also: Gastroenterology, Crohn's disease

Commercial Usage: Ulcerative Colitis

Domain	Title
References	The 2002 Official Patient's Sourcebook on Ulcerative Colitis (reference) (more reference examples)

Books	The Surgical Management of Crohn's Disease & Ulcerative Colitis (reference) (more book examples)
Source: compiled by the editor from various references; see credits.

Non-Fiction Usage: Ulcerative Colitis

Subject	Topic	Quote
Health		Surgery is the only cure for ulcerative colitis. (references)
		Most people with ulcerative colitis will never need to have surgery. (references)
		This procedure is becoming increasingly common for ulcerative colitis. (references)
Source: compiled by the editor from ICON Group International, Inc.; see credits.

Frequency of Internet Keywords: Ulcerative Colitis

Modern Translation: Ulcerative Colitis

Language		Translations for "ulcerative colitis"; alternative meanings/domain in parentheses.
Danish		ulceroes colit, colitis ulcerosa. (various references)

Dutch		colitis ulcerosa, colitis ulcerativa. (various references)

French		recto-colite hémorragique, colite ulcéreuse. (various references)

German		geschwürige Proktokolitis, Colitis ulcerosa. (various references)

Greek		ελκώδης κολίτιδα. (various references)

Italian		colite ulcerosa, colite ulcerativa. (various references)

Pig Latin		erativeulcay olitiscay

Portuguese		colite ulcerosa. (various references)

Spanish		colitis ulcerosa. (various references)
Source: compiled by the editor from various translation references.

Anagrams: Ulcerative Colitis

Scrabble® Enable2K-Verified Anagrams
	Words within the letters "a-c-c-e-e-i-i-i-l-l-o-r-s-t-t-u-v"
	-3 letters: collectivities.
	-4 letters: verticalities.
	-5 letters: clavieristic, cocultivates, coercivities, collectivise, collectivist, creativities, illiteracies, illustrative, literalistic, literalities, reactivities, recultivates, relativistic, relativities, ultraviolets, verticillate, virtualities, volatilities.
Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.

Expression	Frequency per Day	Expression	Frequency per Day
ulcerative colitis	919	ulcerative colitis alternative treatment	3
ulcerative colitis diet	52	ulcerative colitis arthritis	3
symptom of ulcerative colitis	22	ulcerative colitis nutrition	3
ulcerative colitis treatment	20	ulcerative colitis and smoking	3
ulcerative colitis medication	9	ulcerative colitis in child	2
ulcerative colitis pregnancy	9	recipe for ulcerative colitis	2
ulcerative colitis cure	8	ulcerative colitis child	2
ulcerative colitis surgery	8	alcohol ulcerative colitis	2
ulcerative colitis food	7	cause of ulcerative colitis	2
ulcerative colitis picture	5	ulcerative colitis and alternative medicine	2
remicade and ulcerative colitis	4	chronic ulcerative colitis	2
crohns disease ulcerative colitis	4	ulcerative colitis foundation	2
ulcerative colitis a good diet	4	ulcerative colitis natural treatment	2
pediatric ulcerative colitis	3	imuran ulcerative colitis	2
Source: compiled by the editor from various references; see credits.

Ulcerative Colitis

Definition: Ulcerative Colitis