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Superoxide Dismutase

Definition: Superoxide Dismutase

Superoxide Dismutase

Noun

1. An enzyme that catalyzes the conversion of superoxide into hydrogen peroxide and oxygen; "oxygen free radicals are normally removed in our bodies by the superoxide dismutase enzymes".

Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved.
 


Specialty Definition: Superoxide Dismutase

DomainDefinition

Health

An oxidoreductase that catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide. EC 1.15.1.1. (references)

Medicine

Enzyme that catalyzes the reduction of the superoxide radical to hydrogen peroxide. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Specialty Definition: Superoxide dismutase

(From Wikipedia, the free Encyclopedia)

The enzyme superoxide dismutase , or SOD, catalyzes the dismutation of superoxide into oxygen and hydrogen peroxide:

There are at least three forms of superoxide dismutase in nature. Human erythrocytes contain an SOD enzyme with divalent copper and divalent zinc (bovine erythrocyte: PDB 1SXA, EC 1.15.1.1). Chicken liver mitochondria and E. coli contain a form with trivalent manganese (human mitochondrion: PDB 1ABM, EC 1.15.1.1). E. coli also contains a form of the enzyme with trivalent iron ( PDB 1ISA, EC 1.15.1.1). The Cu-Zn enzyme is a dimer of molecular weight 32,500. The two subunits are joined by a disulfide bond.

Although the enzyme isn't especially fast relative to the spontaneous dismutation of superoxide, the ability of the enzyme to provide some protection to organisms is shown by the existence of a motor neuron disease in individuals who have point mutations in SOD and by the finding that the absence of SOD may lead to a form of anemia.

A short but substantive overview of SOD and its literature can be found here.

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Superoxide dismutase."

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Synonym: Superoxide Dismutase

Synonym: SOD (n). (additional references)

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Crosswords: Superoxide Dismutase

English words defined with "superoxide dismutase": sod. (references)
Specialty definitions using "superoxide dismutase": Superoxides. (references)

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Commercial Usage: Superoxide Dismutase

DomainTitle

Books

  • Biometals and Ligands for Anticancer Drug Design: Molecular Mechanisms of Superoxide Dismutase Models Antitumor Effects (reference)

  • Fifth Conference on Superoxide and Superoxide Dismutase (reference)

  • Methods in Enzymology: Superoxide Dismutase (Methods in Enzymology, Vol 349) (reference)

  • Oxy Radicals and Their Scavenger Systems: Proceedings of the Third International Conference on Superoxide and Superoxide Dismutase, Ellenville, New y (reference)

    (more book examples)

Source: compiled by the editor from various references; see credits.

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Non-Fiction Usage: Superoxide Dismutase

SubjectTopicQuote

Health

Enzymes like superoxide dismutase (SOD) and catalase can disarm the damaging oxygen molecules. (references)

About 20 percent of all familial cases result from a specific genetic defect that leads to mutation of the enzyme known as superoxide dismutase 1 (SOD1). (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Expression: Superoxide Dismutase

Expression using "superoxide dismutase": polyethylene glycol superoxide dismutase. Additional references.

Source: compiled by the editor from various references; see credits.

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Frequency of Internet Keywords: Superoxide Dismutase

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

superoxide dismutase

51
Source: compiled by the editor from various references; see credits.

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Modern Translation: Superoxide Dismutase

Language Translations for "superoxide dismutase"; alternative meanings/domain in parentheses.

Danish

  

superoxiddismutase. (various references)

   

Dutch

  

superoxide-dismutase. (various references)

   

Finnish

  

superoksididismutaasi, SOD. (various references)

   

French

  

superoxyde dismutase (super oxide dismutase), SOD (super oxide dismutase). (various references)

   

German

  

Hyperoxid-Dismutase. (various references)

   

Greek 

  

δισμουτάση του υπεροξειδίου. (various references)

   

Italian

  

superossido dismutasi, SOD (super oxide dismutase). (various references)

   

Pig Latin

  

uperoxidesay ismutaseday

   

Portuguese

  

superóxido-dismutase, dismutase do superóxido. (various references)

   

Spanish

  

superóxido dismutasa, SOD. (various references)

   

Swedish

  

superoxiddismutas. (various references)

Source: compiled by the editor from various translation references.

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INDEX

1. Definition
2. Synonyms
3. Crosswords
4. Usage: Commercial 		5. Quotations: Non-fiction
6. Expressions
7. Expressions: Internet
8. Translations: Modern 		9. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.