Copyright © Philip M. Parker, INSEAD. Terms of Use.

| Domain | Definition |
Health | A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl. (references) |
Medicine | Substance that blocks the breakdown of dopamine, thus preserving its availability in the striatum. Source: European Union. (references) |
Source: compiled by the editor from various references; see credits. | |
| Domain | Title |
Books | |
Source: compiled by the editor from various references; see credits. | |
| Subject | Topic | Quote |
Health | When selegiline is given with levodopa, it appears to enhance and prolong the response to levodopa and thus may reduce wearing-off fluctuations. (references) | |
For instance, it was from animal studies that researchers discovered that the drug selegiline can prevent the toxic effects of MPTP. This discovery helped spark interest in studying selegiline as a preventive treatment in humans. (references) | ||
Selegiline inhibits the activity of the enzyme monoamine oxidase B (MAO-B), the enzyme that metabolizes dopamine in the brain, delaying the breakdown of naturally occurring dopamine and of dopamine formed from levodopa and also provides mild symptomatic relief from parkinsonism in-and-of itself. (references) | ||
Source: compiled by the editor from ICON Group International, Inc.; see credits. | ||
| The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com. |
| Expression | Frequency per Day |
selegiline | 49 |
deprenyl l selegiline | 5 |
patch selegiline | 3 |
depression selegiline | 2 |
eldepryl selegiline | 2 |
| Source: compiled by the editor from various references; see credits. | |
| Language | Translations for "SELEGILINE"; alternative meanings/domain in parentheses. | ||||||||||||||||||||||
Danish | selegilin. (various references) | ||||||||||||||||||||||
Dutch | selegiline. (various references) | ||||||||||||||||||||||
Finnish | selegiliini. (various references) | ||||||||||||||||||||||
French | sélégiline, L-déprényl. (various references) | ||||||||||||||||||||||
German | Selegilin (deprenyl), L-Deprenyl (deprenyl). (various references) | ||||||||||||||||||||||
Italian | selegilina (deprenyl). (various references) | ||||||||||||||||||||||
Pig Latin | elegilinesay selegilina. (various references) selegilina (deprenyl), deprenilo (deprenyl). (various references) selegilin. (various references) | ||||||||||||||||||||||
Scrabble® Enable2K-Verified Anagrams | |
| Words within the letters "e-e-e-g-i-i-l-l-n-s" | |
-3 letters: elegies, elegise, gillies, nellies, seeling, selling. | |
-4 letters: enisle, ensile, gelees, genies, gillie, ingles, isling, lieges, lilies, nellie, nielli, seeing, senile, signee, sileni, single. | |
-5 letters: geese, gelee, genes, genie, genii, gills, glees, glens, ingle, leges, lenes, lenis, lense, liege, liens, lines, lings, lisle, nills, nisei, segni, seine, selle, sengi, siege, sigil, singe, sling, snell. | |
| Words containing the letters "e-e-e-g-i-i-l-l-n-s" | |
+3 letters: intelligences. | |
+4 letters: belligerencies, intelligencers, vitellogenesis. | |
+5 letters: allergenicities. | |
| Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro. | |
| 1. Usage: Commercial 2. Quotations: Non-fiction 3. Expressions: Internet 4. Translations: Modern | 5. Anagrams 6. Bibliography |
Copyright © Philip M. Parker, INSEAD. Terms of Use.