Copyright © Philip M. Parker, INSEAD. Terms of Use.

SELEGILINE

Specialty Definition: SELEGILINE

DomainDefinition

Health

A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl. (references)

Medicine

Substance that blocks the breakdown of dopamine, thus preserving its availability in the striatum. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Commercial Usage: SELEGILINE

DomainTitle

Books

Source: compiled by the editor from various references; see credits.

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Non-Fiction Usage: SELEGILINE

SubjectTopicQuote

Health

When selegiline is given with levodopa, it appears to enhance and prolong the response to levodopa and thus may reduce wearing-off fluctuations. (references)

For instance, it was from animal studies that researchers discovered that the drug selegiline can prevent the toxic effects of MPTP. This discovery helped spark interest in studying selegiline as a preventive treatment in humans. (references)

Selegiline inhibits the activity of the enzyme monoamine oxidase B (MAO-B), the enzyme that metabolizes dopamine in the brain, delaying the breakdown of naturally occurring dopamine and of dopamine formed from levodopa and also provides mild symptomatic relief from parkinsonism in-and-of itself. (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Frequency of Internet Keywords: SELEGILINE

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

selegiline

49

deprenyl l selegiline

5

patch selegiline

3

depression selegiline

2

eldepryl selegiline

2
Source: compiled by the editor from various references; see credits.

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Modern Translation: SELEGILINE

Language Translations for "SELEGILINE"; alternative meanings/domain in parentheses.

Danish

  

selegilin. (various references)

   

Dutch

  

selegiline. (various references)

   

Finnish

  

selegiliini. (various references)

   

French

  

sélégiline, L-déprényl. (various references)

   

German

  

Selegilin (deprenyl), L-Deprenyl (deprenyl). (various references)

   

Italian

  

selegilina (deprenyl). (various references)

   

Pig Latin

  

elegilinesay

   

Portuguese

  

selegilina. (various references)

   

Spanish

  

selegilina (deprenyl), deprenilo (deprenyl). (various references)

   

Swedish

  

selegilin. (various references)

Source: compiled by the editor from various translation references.

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Anagrams: SELEGILINE

Scrabble® Enable2K-Verified Anagrams

Words within the letters "e-e-e-g-i-i-l-l-n-s"

-3 letters: elegies, elegise, gillies, nellies, seeling, selling.

-4 letters: enisle, ensile, gelees, genies, gillie, ingles, isling, lieges, lilies, nellie, nielli, seeing, senile, signee, sileni, single.

-5 letters: geese, gelee, genes, genie, genii, gills, glees, glens, ingle, leges, lenes, lenis, lense, liege, liens, lines, lings, lisle, nills, nisei, segni, seine, selle, sengi, siege, sigil, singe, sling, snell.

 Words containing the letters "e-e-e-g-i-i-l-l-n-s"
 

+3 letters: intelligences.

 

+4 letters: belligerencies, intelligencers, vitellogenesis.

 

+5 letters: allergenicities.

Source: compiled by the editor from various references; see credits.

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INDEX

1. Usage: Commercial
2. Quotations: Non-fiction
3. Expressions: Internet
4. Translations: Modern
5. Anagrams
6. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.