Peptic Ulcer

Domain	Definitions
Environment	An ulceration of the mucous membrane of the esophagus, stomach or duodenum, caused by the action of the acid gastric juice. Source: European Union. (references)
Health	Ulcer that occurs in those portions of the alimentary tract which come into contact with gastric juice containing pepsin and acid. It occurs when the amount of acid and pepsin is sufficient to overcome the gastric mucosal barrier. (references)
Source: compiled by the editor from various references; see credits.

Specialty Definition: Peptic ulcer

Peptic ulcer is a non-malignant ulcer of the stomach (called gastric ulcer) or duodenum (called duodenal ulcer). By far most instances are now known to be be due to Helicobacter pylori, a spiral-shaped bacteria that lives in the acid environment of the stomach. These ulcers can also be caused or worsened by drugs such as Aspirin.

Ulcers were once attributed to stress, tobacco smoking, blood groups, spices and a large array of strange things. Some of these factors are possibly minor contributory factors.

In Western countries the age-related prevalence of Helicobacter infections roughly matches age (i.e., 20% at age 20, 30% at age 30, 80% at age 80 etc). Prevalence is higher in third world countries. Transmission is by food and human contact, sharing food utensils etc.

A minority of cases of Helicobacter infection will eventually lead to an ulcer and a larger proportion of people will get non-specific discomfort or gastritis.

Anti-acid treatments such as cimetidine, ranitidine and antacids may reduce symptoms but will not clear the infection. Bismuth compounds may actually reduce or even clear organisms. The most effective treatments are combinations of antibiotics (Erythromycin, Ampicillin, Tetracycline, Metronidazole) and proton pump inhibitors.

Treatment of Helicobacter usually leads to clearing of infection, relief of symptoms and eventual healing of ulcers. Recurrence of infection can occur and retreatment may be required.

The diagnosis of Helicobacter can be by:

Biopsy
Breath tests
Direct culture
Direct detection of urease activity.

Rarely now, some ulcers perforate and require surgery.

The possibility of other causes of ulcers, notably malignancy needs to be kept in mind.

Commercial Usage: Peptic Ulcer

Domain	Title
References	The 2002 Official Patient's Sourcebook on Peptic Ulcer (reference) (more reference examples)

Books	Famotidine: A Further Development in the Modern Treatment of Peptic Ulcer Disease (Digestion, Vol 32) (reference) Campylobacter Pylori in Gastritis and Peptic Ulcer Disease (reference) Antacids in Peptic Ulcer Disease State of the Art (Perspectives in Digestive Disease Series) (reference) Peptic Ulcer & Its Drug Causation: The Role of Non-Steroidal Anti-Inflammatory Drugs (reference) Diagnosis and Management of Peptic Ulcer Disease (2nd Edition) (reference) (more book examples)
Source: compiled by the editor from various references; see credits.

Non-Fiction Usage: Peptic Ulcer

Subject	Topic	Quote
Health		A peptic ulcer is a sore in the lining of the stomach or duodenum. (references)
		Antagonists of this receptor proved to be safe and effective therapy for peptic ulcer disease. (references)
		If you have a peptic ulcer and have not been tested for H. pylori infection, talk to your doctor. (references)
Source: compiled by the editor from ICON Group International, Inc.; see credits.

Expressions: Peptic Ulcer

Frequency of Internet Keywords: Peptic Ulcer

Modern Translations: Peptic Ulcer

Language		Translations for "peptic ulcer"; alternative meanings/domain in parentheses.
Bulgarian		пептична язва. (various references)

Danish		ulcus pepticum, mavesår (gastric ulcer, ventricular ulcer). (various references)

Dutch		ulcus pepticum. (various references)

French		peptique (ulcère-), ulcère peptique. (various references)

German		Magengeschwür (gastric ulcer, stomach ulcer, ulcerated stomach, ventricular ulcer). (various references)

Hungarian		gyomorfekély (gastric ulcer, stomachic ulcer). (various references)

Italian		ulcera peptica. (various references)

Manx		askaid pheptagh. (various references)

Pig Latin		epticpay erulcay

Portuguese		úlcera péptica. (various references)

Russian		язвенная болезнь, язва желудка и двенадцатиперстной кишки. (various references)

Turkish		mide ülseri (gastric ulcer), ülser (gastric ulcer, ulcer). (various references)
Source: compiled by the editor from various translation references.

Misspellings: Peptic Ulcer

Anagrams: Peptic Ulcer

Scrabble® Enable2K-Verified Anagrams
	Words within the letters "c-c-e-e-i-l-p-p-r-t-u"
	-3 letters: electric, eupeptic, reticule.
	-4 letters: circlet, clipper, cripple, culprit, cupeler, cuppier, cuprite, cuticle, epicure, eucrite, lecture, leucite, percept, perlite, picture, precept, precipe, prelect, prepuce, puerile, pulpier, receipt, reptile, reticle, ripplet, tiercel, tippler, utricle.
	-5 letters: ceiler, cerite, circle, cleric, cretic, cultic, cupper, cupric, curite, cutler, lipper, luetic, pectic, peepul, pelite, pelter, peptic, petrel, piecer, pierce.
Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.

Alternative Orthography: Peptic Ulcer

Hexadecimal (or equivalents, 770AD-1900s) (references)

50 65 70 74 69 63 55 6C 63 65 72

Leonardo da Vinci (1452-1519; backwards) (references)

Binary Code (1918-1938, probably earlier) (references)

01010000 01100101 01110000 01110100 01101001 01100011 00100000 01010101 01101100 01100011 01100101 01110010

HTML Code (1990) (references)

&#80 &#101 &#112 &#116 &#105 &#99 &#32 &#85 &#108 &#99 &#101 &#114

ISO 10646 (1991-1993) (references)

0050 0065 0070 0074 0069 0063 0055 006C 0063 0065 0072

Encryption (beginner's substitution cypher): (references)

Expression	Frequency per Day
peptic ulcer	352
peptic ulcer disease	50
peptic ulcer symptom	35
diet peptic ulcer	15
peptic ulcer treatment	10
peptic ulcer disease symptom	3
bleeding peptic ulcer	2
diagnosis of peptic ulcer	2
Source: compiled by the editor from various references; see credits.

Expressions using "peptic ulcer": Peptic Ulcer Disease (PUD) ♦ Peptic Ulcer Hemorrhage ♦ Peptic Ulcer Perforation. Additional references.
Source: compiled by the editor from various references; see credits.

Misspellings
	"Peptic Ulcer" is suggested in spellcheckers for the following: pepic ulcer. (additional references)
Source: compiled by the editor, based on several corpora (additional references).

Peptic Ulcer

Definition: Peptic Ulcer

Peptic Ulcer

Noun

Specialty Definitions: Peptic Ulcer

Specialty Definition: Peptic ulcer

Synonym: Peptic Ulcer

Crosswords: Peptic Ulcer

Commercial Usage: Peptic Ulcer

References

Books

Non-Fiction Usage: Peptic Ulcer

Expressions: Peptic Ulcer

Frequency of Internet Keywords: Peptic Ulcer

Modern Translations: Peptic Ulcer

Bulgarian

Danish

Dutch

French

German

Hungarian

Italian

Manx

Pig Latin

Portuguese

Russian

Turkish

Misspellings: Peptic Ulcer

Misspellings

Anagrams: Peptic Ulcer

Scrabble® Enable2K-Verified Anagrams

Alternative Orthography: Peptic Ulcer

50 65 70 74 69 63 55 6C 63 65 72

01010000 01100101 01110000 01110100 01101001 01100011 00100000 01010101 01101100 01100011 01100101 01110010

&#80 &#101 &#112 &#116 &#105 &#99 &#32 &#85 &#108 &#99 &#101 &#114

0050 0065 0070 0074 0069 0063 0055 006C 0063 0065 0072

50718286756925578697184

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