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MONOCLONAL ANTIBODIES

Specialty Definition: MONOCLONAL ANTIBODIES

DomainDefinition

Environment

1. Man-made (anthropogenic) clones of a molecule, produced in quantity for medical or research purposes. 2. Molecules of living organisms that selectively find and attach to other molecules to which their structure conforms exactly. This could also apply to equivalent activity by chemical molecules. (Also called MABs and MCAs). (references)

Health

Laboratory-produced substances that can locate and bind to cancer cells wherever they are in the body. Many monoclonal antibodies are used in cancer detection or therapy; each one recognizes a different protein on certain cancer cells. Monoclonal antibodies can be used alone, or they can be used to deliver drugs, toxins, or radioactive material directly to a tumor. (references)

Medicine

An antibody produced by culturing a single type of cell. It therefore consists of a single species of immunoglobulin molecules. Such cell lines are produced by fusing cells capable of forming antibodies with myeloma cells which are capable of sustained division and growth. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Abbreviations & Acronyms: MONOCLONAL ANTIBODIES

The following table is compiled from various sources, across various languages. When English abbreviations or acronyms come from a non-English source, this is noted.
EntrySourceExpressionField
MoAbEnglishMonoclonal AntibodiesMedicine

Source: compiled by the editor, based on several corpora (additional references).

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Synonym: MONOCLONAL ANTIBODIES

Synonym by domain: mab (medicine).

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Crosswords: MONOCLONAL ANTIBODIES

Specialty definitions using "MONOCLONAL ANTIBODIES": 2IT-BAD monoclonal antibody 170A33 monoclonal antibody, Antigenic Modulation, Antigens, CD, Antigens, CD15, Antigens, Neoplasm, Antigens, Tumor-Associated, CarbohydrateCampath-1H, CC-49 monoclonal antibody, cetuximab, coactivated T cellsdaclizumabedrecolomabgemtuzumab ozogamicinIDEC-Y2B8 monoclonal antibody, Immunoblotting, Immunoconjugates, Immunotoxinsmonoclonal antibody 3F8, muJ591 monoclonal antibody, muromonab-CD3 monoclonal antibodypM-81 monoclonal antibody, Prost 30 monoclonal antibodyrituximabtrastuzumab. (references)

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Commercial Usage: MONOCLONAL ANTIBODIES

DomainTitle

Books

  • Applications And Engineering Of Monoclonal Antibodies (reference)

  • Clinical Applications of Monoclonal Antibodies (reference)

  • Monoclonal Antibodies and Functional Cell Lines: Progress and Applications (reference)

    (more book examples)

Source: compiled by the editor from various references; see credits.

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Photo Album: MONOCLONAL ANTIBODIES

ThumbnailDescription & CreditThumbnailDescription & Credit

Radiolabeled monoclonal antibodies confirm that this patient's cutaneous t-cell lymph cancer involves the lymph nodes and skin. The antibodies collect in the cancerous lymph nodes of the armpits, neck and groin and a strong outline of the patient's body verifies skin involvement. The liver and spleen are darkened, too, because it is normal for these organs to collect the antibodies. See artwork: GA-17. Credit: Unknown photographer/artist.

Pictured are two researchers on a laboratorry setting. They are looking at slides on a light box. These are slides of cultures of cells that make monoclonal antibodies. These are grown in a lab and the researchers are analyzing the products to select the most promising of them. Credit: Linda Bartlett (photographer).

Shown is a stack of covered, prepared wells in a laboratory setting. They are being held by rubber-gloved hands. Cells that make monoclonal antibodies are sorted and grown in wells. These are trays of such wells prepared for research. Credit: Linda Bartlett (photographer).

Shown is the hand of a lab technician bathing some prepared slides in a solution. This technician is involved in the preparation of slides of monoclonal antibodies for researchers. These highly specific cells shown are those labeling human breast cancer. Credit: Linda Bartlett (photographer).

Pictured is a laboratory setting. A technician wearing a white lab coat and head covering, rubber gloves, is holding a large glass roller bottle and looking into it. A red liquid is visible in the tilted roller bottle. This process is the growing of monoclonal antibodies. They can be grown in unlimited quantities in bottles in the lab. Several shots available. Credit: Linda Bartlett (photographer).

Several shots of a scientist in a laboratory setting, wearing a white coat and performing a test. Only his hands are visible in some of the photos. The scientist is sorting B-cells taken from the bone marrow of a patient with Lupus disease. The Lupus antibody-producing cell is isolated in a well, to be fused with a cancerous mouse myeloma B-cell, producing a hybridoma. Hybridomas produce identical monoclonal antibodies in large quantities and indefinitely. Credit: Linda Bartlett (photographer).

Technician Carolyn Johnson uses monoclonal antibodies to confirm E. coli O157:H7 presence in cattle fecal samples. P. Credit: USDA ARS News; photo by Keith Weller..

  

Source: pictures compiled by the editor from various references; see picture credits.

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Non-Fiction Usage: MONOCLONAL ANTIBODIES

SubjectTopicQuote

Health

In addition, monoclonal antibodies may be used to detect rabies virus variants. (references)

Scientists are now producing monoclonal antibodies against tumor cell antigens and testing their usefulness. (references)

Monoclonal antibodies are identical, laboratory-produced antibodies that are highly specific for a single antigen. (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Modern Translation: MONOCLONAL ANTIBODIES

Language Translations for "MONOCLONAL ANTIBODIES"; alternative meanings/domain in parentheses.

Danish

  

monoklonale antistoffer (mca). (various references)

   

Dutch

  

monoklonale antilichamen (mca), mca (mca). (various references)

   

Finnish

  

monoklonaalinen vasta-aine (mca). (various references)

   

French

  

anticorps monoclonaux, ACM. (various references)

   

German

  

monoklonale Antikörper (mca). (various references)

   

Greek 

  

μονοκλωνικά αντισώματα (mca). (various references)

   

Italian

  

anticorpi monoclonali (mca). (various references)

   

Pig Latin

  

onoclonalmay antibodiesay.(various references)

   

Portuguese

  

anticorpos monoclonais (mca). (various references)

   

Spanish

  

anticuerpo monoclonal (mca). (various references)

   

Swedish

  

monoklonala antikroppar (mca). (various references)

Source: compiled by the editor from various translation references.

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INDEX

1. Synonyms
2. Crosswords
3. Usage: Commercial
4. Images: Photo Album
5. Quotations: Non-fiction
6. Translations: Modern
7. Abbreviations
8. Acronyms
9. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.