Iridocyclitis

Iridocyclitis, also known as anterior uveitis, is a condition in which the uvea of the eye suffers inflammation.

Symptoms include photophobia, redness, watering of the eyes, lacrimation, miosis, and blurred vision. Iridocyclitis is usually caused by direct exposure of the eyes to chemicals, particularly lacrimators. It can be effectively treated with tropane alkaloids or steroids.

There are six classifications of iridocyclitis.

Acute or Chronic

Acute: sudden symptomatic onset, lasting no more than six weeks.

Chronic: Persisting for more than six weeks, possibly asymptomatic. Chronic iridocyclitis is usually associated with systemic disorders including ankylosing spondylitis, Behçet's syndrome, inflammatory bowel disease, juvenile rheumatoid arthritis, Reiter's syndrome, sarcoidosis, syphilis, tuberculosis, and Lyme disease.

Exogenous or Endogenous

Exogenous: related to external damage to the uvea or invasion of external microbes.

Endogenous: related to internal microbes.

Granulomatous or Non-granulomatous

Granulomatous: accompanied by large keratotic precipitates.

Non-granulomatous: accompanied by smaller keratotic precipitates.

Treatment

To immobilize the iris and decrease pain, one may find tropane alkaloids effective, particularly scopolamine and atropine in .25% and 1% concentrations respectively. Topical steroids may be used to decrease inflammation, particularly prednisolone and dexamethasone.

See also: inflammation, uvea