Copyright © Philip M. Parker, INSEAD. Terms of Use.

ADRENERGIC RECEPTOR

Specialty Definition: ADRENERGIC RECEPTOR

DomainDefinition

Medicine

Receptors specifically sensitive to and operated by adrenaline and/or noradrenaline and related sympathomimetic drugs. Adrenoreceptor is an alternative name. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

Top     

Specialty Definition: Adrenergic receptor

(From Wikipedia, the free Encyclopedia)

An adrenergic receptor (or adrenoceptor) is a cell membrane protein that is the target of catecholamines. Adrenergic receptors specifically bind the catecholamines adrenaline and noradrenaline (also called epinephrine and norepinephrine) and are activated by these.

Many cells possess these receptors, and the binding of an agonist will generally cause the cell to respond in a flight-fight manner. For instance, the heart will start beating quicker and the pupils will dilate.

Sub-types of adrenergic receptors

There are several types of adrenergic receptors, but there are five main groups:

Alpha-1 receptors

In blood vessels these cause vasoconstriction. Blood vessels with alpha-1 receptors are present in the skin and the gastrointestinal system, and during the flight-or-fight response there is decreased blood flow to these organs. This is the reason people can appear pale when they've been frightened.

Alpha-2 receptors

When an agonist binds to an α2-receptor, cyclic AMP levels within the cell decrease. These are found on pre-synaptic nerve terminals.

Beta-1 receptors

These are present in heart tissue, and cause an increased heart rate by acting on the cardiac pacemaker cells. Many beta-blockers for treatment of angina will only affect these receptors and not the beta-2 receptors.

Beta-2 receptors

These are in the vessels of skeletal muscle, and cause vasodilation, which allows more blood to flow to the muscles, and reduces total peripheral resistance. These tend to work with adrenaline (epinephrine), but not noradrenaline (norepinephrine).

Beta-2 receptors are also in bronchial smooth muscle, and cause bronchodilation when activated. Anti-asthma drugss, such as salbutamol (Ventolin) work by binding to β2 receptors.

Non-selective beta-blocking drugs, such as propanolol (Inderal), can represent a risk to people with asthma by blocking the beta-2 receptors, causing bronchoconstriction.

Beta-3 receptors

Beta-3 receptors are present in adipose tissue and are thought to have a role in the regulation of lipid metabolism.

External links

Brief overview of functions of the beta-3 receptor

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Adrenergic receptor."

Top     

Crosswords: ADRENERGIC RECEPTOR

Specialty definitions using "ADRENERGIC RECEPTOR": Ketanserin. (references)

Top     

Commercial Usage: ADRENERGIC RECEPTOR

DomainTitle

Books

  • Adrenergic Receptor Protocols (Methods in Molecular Biology, 136) (reference)

    (more book examples)

Source: compiled by the editor from various references; see credits.

Top     

Expressions: ADRENERGIC RECEPTOR

Hypenated Usage

Ending with "ADRENERGIC RECEPTOR": alpha-adrenergic receptor, beta-adrenergic receptor.

Source: compiled by the editor from various references; see credits.

Top     

Frequency of Internet Keywords: ADRENERGIC RECEPTOR

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

adrenergic receptor

2
Source: compiled by the editor from various references; see credits.

Top     

Modern Translation: ADRENERGIC RECEPTOR

Language Translations for "ADRENERGIC RECEPTOR"; alternative meanings/domain in parentheses.

Danish

  

adrenoceptor (adrenoceptor, adrenoreceptor), adrenerg receptor (adrenoceptor, adrenoreceptor). (various references)

   

Dutch

  

adrenerge receptor (adrenoceptor, adrenoreceptor). (various references)

   

Finnish

  

adrenerginen reseptori (adrenoceptor, adrenoreceptor). (various references)

   

French

  

adrénorécepteur (adrenoceptor, adrenoreceptor), récepteur adrénergique (adrenoceptor, adrenoreceptor). (various references)

   

German

  

adrenerger Rezeptor (adrenoceptor, adrenoreceptor). (various references)

   

Greek 

  

αδρενεργικός υποδοχέας (adrenoceptor, adrenoreceptor). (various references)

   

Italian

  

recettore adrenergico (adrenoceptor, adrenoreceptor). (various references)

   

Pig Latin

  

adrenergicay eceptorray

   

Portuguese

  

receptor adrenérgico (adrenoceptor, adrenoreceptor). (various references)

   

Spanish

  

receptor adrenérgico (adrenoceptor, adrenoreceptor). (various references)

   

Swedish

  

adrenerg receptor (adrenoceptor, adrenoreceptor). (various references)

Source: compiled by the editor from various translation references.

Top     

Anagrams: ADRENERGIC RECEPTOR

Scrabble® Enable2K-Verified Anagrams

Words within the letters "a-c-c-d-e-e-e-e-g-i-n-o-p-r-r-r-r-t"

-5 letters: catercornered.

Source: compiled by the editor from various references; see credits.

SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.

Top     



INDEX

1. Crosswords
2. Usage: Commercial
3. Expressions
4. Expressions: Internet
5. Translations: Modern
6. Anagrams
7. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.