Copyright © Philip M. Parker, INSEAD. Terms of Use.

| Domain | Definition |
Health | A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins. (references) |
Source: compiled by the editor from various references; see credits. | |
Crosswords: TRANSFORMING GROWTH FACTOR BETA |
| Specialty definitions using "TRANSFORMING GROWTH FACTOR BETA": Receptors, Transforming Growth Factor beta ♦ Transforming Growth Factors. (references) |
| Subject | Topic | Quote |
Health | Protein antigen feeding, discussed above, may release transforming growth factor beta (TGF), a protective cytokine that inhibits or regulates the activity of certain immune cells. (references) | |
Source: compiled by the editor from ICON Group International, Inc.; see credits. | ||
| Language | Translations for "TRANSFORMING GROWTH FACTOR BETA"; alternative meanings/domain in parentheses. | ||||||||||
Dutch | transforming growth factor-bèta, TGF-bèta. (various references) | ||||||||||
French | facteur de croissance transformant bêta, facteur de croissance bêta transformant. (various references) | ||||||||||
Italian | fattore di crescita trasformante beta. (various references) | ||||||||||
Pig Latin | ansformingtray owthgray actorfay etabay factor de crecimiento beta transformador. (various references) | ||||||||||
Copyright © Philip M. Parker, INSEAD. Terms of Use.