Sepsis

Definition: Sepsis

Sepsis

Noun

1. The presence of pus-forming bacteria or their toxins in the blood or tissues.

Date "sepsis" was first used: 1876. (references)

Etymology: Sepsis \Sep"sis\, noun. [New Latin expression, from the Greek expression putrefaction.]. (Websters 1913)

Domain	Definitions
Health	The presence of bacteria in the bloodstream. (references)
Medicine	A term originally used to denote a putrefactive process in the body, but now usually referring to infection with pyogenic micro-organisms ; a genus of Diptera ; the severe type of infection in which the blood stream is invaded by large numbers of the causal bacteria which multiply in it and spread. Source: European Union. (references)
Source: compiled by the editor from various references; see credits.

Sepsis is a life-threatening condition caused by the immune response of an organism to severe infection. Sepsis is characterized by overwhelming systemic (i.e. not localised) inflammation. It is often associated with coagulation disorders and dysfunction of the circulatory system. Even under optimal treatment, dysfunction of many organ systems may progress to multiple organ failure and eventually death.

Sepsis is particulary common and dangerous in elderly, immunocompromised, and critically ill patients, where it is a major cause of death in intensive care units worldwide. In the United States, sepsis is the leading cause of death in non-coronary ICU patients, while recent 1998 data from the Centers for Disease Control show that it is the 11th leading cause of death overall. Mortality rates ranging from 28 to 50% have been reported for sepsis.

The therapy of sepsis rests on antibiotic (and in some cases, surgical) treatment of the causating infection, fluid replacement, adequate nutrition (including parenteral nutrition), and appropriate support for organ dysfunction. This may include hemodialysis in renal failure, mechanical ventilation in pulmonary dysfunction, transfusion of blood plasma, platelets and coagulation factors to stabilize blood coagulation, and drug and fluid therapy for circulatory failure. Therapeutic strategies aimed at the inflammation process itself have largely failed to improve outcome. However, the infusion of activated Protein C, a coagulation factor, has recently been shown to improve survival in sepsis. Low dose cortisol also seems to be beneficial.

Related conditions

Septicemia (or bacteriemia) is the presence of bacteria in the bloodstream. Septicemia can occur in sepsis and other serious diseases such as infective endocarditis, but it may also be a harmless and transient condition.
SIRS (Systemic inflammatory response syndrome) is associated with a variety of causes such as severe trauma, burns, or shock. In its clinical appearance SIRS may be indistinguishable from sepsis, but a causating infection is by definition not involved.

Context	Synonyms within Context (source: adapted from Roget's Thesaurus).
Disease	Taint, pollution, infection, sepsis, septicity, infestation; epidemic, pandemic, endemic, epizootic; murrain, plague, pestilence, pox.
Source: adapted from Roget's Thesaurus.

Crosswords: Sepsis

English words defined with "sepsis": clean ♦ uninfected. (references)

Specialty definitions using "sepsis": Bacterial Translocation ♦ Fungemia ♦ Water-washed disease. (references)

Etymologies containing "sepsis": Antisepsis, Asepsis. (references)

Non-English Usage: "Sepsis" is also a word in the following languages with English translations in parentheses.

Albanian (sepsis), German (blood poisoning, sepsis, septicaemia, septicemia), Swedish (sepsis, septicaemia).

Domain	Title
Books	Controversies in Surgical Sepsis (reference) Emergency Surgery: Trauma, Shock, Sepsis, Burns (reference) Sepsis and Multiorgan Failure (reference) Shock, Sepsis, and Organ Failure: Brain Damage Secondary to Hemorrhagic-Traumatic Shock, Sepsis, and Traumatic Brain Injury (reference) Trauma, Sepsis, and Shock: The Physiological Basis of Therapy (Science and Practice of Surgery Series, No 15) (reference) (more book examples)
Source: compiled by the editor from various references; see credits.

Subject	Topic	Quote
Health		Occasionally can progress to sepsis. (references)
		Sepsis, pneumonia, and meningitis are the most common problems. (references)
		This pathogen emerged in the 1970s as the most common cause of sepsis in newborns. (references)
Source: compiled by the editor from ICON Group International, Inc.; see credits.

"Sepsis" is generally used as a noun (singular) -- approximately 100.00% of the time. "Sepsis" is used about 80 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted)

Parts of Speech	Percent	Usage per 100 Million Words	Rank in English
Noun (singular)	100%	80	37,112

Expression using "sepsis": Sepsis Syndrome. Additional references.
Source: compiled by the editor from various references; see credits.

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.

Language		Translations for "sepsis"; alternative meanings/domain in parentheses.
Albanian		sepsis, infektim i përgjithshëm, gjendje seeptike. (various references)

Arabic		‏تعفن الدم, ‏خمج الدم. (various references)

Bulgarian		сепсис, отравяне (disinterment, intoxication, poisoning). (various references)

Czech		sepse, otrava krve (blood poisoning). (various references)

Danish		septikaemi (blood poisoning, septicaemia, septicemia), sepsis (blood poisoning, septicaemia, septicemia), blodforgiftning (blood poisoning, septicaemia, septicemia). (various references)

Dutch		septikemie (blood poisoning, septicaemia, septicemia), septicemie (blood poisoning, septicaemia, septicemia), septicaemia (blood poisoning, septicaemia, septicemia), sepsis (blood poisoning, septicaemia, septicemia), bloedvergiftiging (blood poisoning, septicaemia, septicemia). (various references)

Finnish		septikemia (blood poisoning, septicaemia, septicemia), sepsis (blood poisoning, septicaemia, septicemia), verenmyrkytys (blood poisoning, blood-poisoning, septicaemia, septicemia). (various references)

French		septicité, septicémie (septicaemia, septicemia), empoisonnement du sang (septicaemia, septicemia), état septique. (various references)

German		Blutvergiftung (blood poisoning, septicaemia, septicemia), sepsis (blood poisoning, septicaemia, septicemia), Fäulnis (decadence, decay, degeneracy, putrefaction, putrescence, rot, rottenness). (various references)

Greek		σήψη (decay, putrefaction, putridity, rot). (various references)

Hebrew		אלוח (contaminated, contamination, infection, pollution, septic), אלח �"�"ם, אלח (contamination, infection). (various references)

Hungarian		vérmérgezés (blood poisoning, septic infection, septicaemia, septicemia). (various references)

Italian		sepsi (blood poisoning, septicaemia, septicemia). (various references)

Manx		molkey (decay; putrefaction, mortify, putrefy, rot, rotting). (various references)

Pig Latin		epsissay

Portuguese		septicemia (blood plague, blood poisoning, septicaemia, septicemia, septicemic plague, siderating plague). (various references)

Russian		сепсис (septicaemia, septicemia). (various references)

Serbo-Croatian		sepsa (septicaemia). (various references)

Spanish		septicemia (blood poisoning, septicaemia, septicemia). (various references)

Swedish		sepsis (septicaemia), blodförgiftning (blood poisoning, septicaemia, toxaemia, toxemia). (various references)

Thai		การติ�"เชื้อแบคทีเรียในร่างกาย. (various references)

Turkish		septisemi (septemia, septicaemia, septicemia), kan zehirlenmesi (blood poisoning, pyaemia, septemia, septicaemia, septicemia, toxaemia, toxemia). (various references)

Ukranian		сепсис (septicaemia, septicemia). (various references)
Source: compiled by the editor from various translation references.

Language	Period	Translations
Greek	700 BCE-300 CE	sepsis. (various references)
Source: compiled by the editor from various references.

Derivations
	Words ending with "sepsis": antisepsis, asepsis. (additional references)
Misspellings
	"Sepsis" is suggested in spellcheckers for the following: epsis, Sansisu, Sarpsis, Selsit, sepis, sepsu, Sesia, sesit, Sibusiso. (additional references)
Source: compiled by the editor, based on several corpora (additional references).

# of Phoneme Matches	Pronunciation	Word(s) rhyming with "sepsis" (pronounced se"psi's)
3	-s i' s	asbestosis, basis, Cassis, electrophoresis, emphasis, endometriosis, lexis, lysis, oasis, osmosis, osteoporosis, paralysis, parenthesis, pertussis, praxis, Pyxis, Telesis.
Source: compiled by the editor (additional references); see credits.

Scrabble® Enable2K-Verified Anagrams
	Direct Anagrams: pisses, speiss.
	Words within the letters "e-i-p-s-s-s"
	-1 letter: sipes, sises, spies.
	-2 letters: pies, piss, psis, seis, sipe, sips.
	-3 letters: ess, pes, pie, pis, psi, sei, sip, sis.
	-4 letters: es, is, pe, pi, si.
	Words containing the letters "e-i-p-s-s-s"
	+1 letter: asepsis, aspises, pissers, plisses, prisses, pussies, skepsis, speises.
	+2 letters: cesspits, despises, disposes, impasses, missteps, passives, pastises, pelisses, persists, poussies, prissies, prossies, psiloses, pussiest, pusslies, slipless, speisses, spinless, suspires.
	+3 letters: apishness, crispness, despisers, dispenses, disperses, disposers, epistases, epistasis, escapisms, escapists, fissipeds, gaposises, gossipers, hipnesses, impresses, misparses, mispoises, misshapes, misspaces, misspeaks, misspells, misspends, pastiness, pertussis, pessaries, pessimism, pessimist, piousness, premisses, pressings, priestess, prissiest, prosiness, psoriases, pursiness, pushiness, pyrosises, sappiness, shipsides, sideslips, sidespins, sidesteps, skepsises, slipcases, slipsoles, soapiness, soppiness, spiceless, spiciness, spikiness, spineless, spininess, spinsters, steapsins, stypsises, surprises, syllepsis, tipsiness, wispiness.
Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.

Hexadecimal (or equivalents, 770AD-1900s) (references)

53 65 70 73 69 73

Leonardo da Vinci (1452-1519; backwards) (references)

American Sign Language (origins from 1620-1817 in Italy and, especially, France) (references)

⁼

Semaphore (1791, in France) (references)

Braille (1829, in France) (references)

Morse Code (1836) (references)

... . .--. ... .. ...

Dancing Men (Sir Arthur Conan Doyle, 1903) (references)

Binary Code (1918-1938, probably earlier) (references)

01010011 01100101 01110000 01110011 01101001 01110011

HTML Code (1990) (references)

&#83 &#101 &#112 &#115 &#105 &#115

ISO 10646 (1991-1993) (references)

0053 0065 0070 0073 0069 0073

British Sign Language (Fingerspelling, BSL; 1992, British Deaf Association Dictionary of British Sign Language) (references)

Encryption (beginner's substitution cypher): (references)

Expression	Frequency per Day	Expression	Frequency per Day
sepsis	501	de sepsis tratamiento	3
sepsis neonatal	49	sepsis syndrome	3
infection sepsis	12	antibioticos en sepsis	3
symptom of sepsis	10	niños sepsis	3
neonatorum sepsis	6	cause sepsis	2
puerperal sepsis	5	definition sepsis	2
sepsis abdominal	5	sepsis septic shock	2
sepsis treatment	4	newborn sepsis	2
in neonates sepsis therapy treatment	4	antioxidantes sepsis y	2
gram negative sepsis	3	catheter malpractice related sepsis	2
pathophysiology sepsis	3	pneumococcal sepsis	2
sepsis severe	3	sepsis sign symptom	2
sepsis shock	3	aspiration pneumonia sepsis	2
sepsis information	3	sepsis staph	2
disfuncion hepatica sepsis y	3	dental sepsis	2
abdominal en enteral nutricion sepsis severa	3	malpractice sepsis	2
neutropenic sepsis	3	de de factores neonatal perinatal riesgo sepsis	2
Source: compiled by the editor from various references; see credits.

Sepsis

Definition: Sepsis

Sepsis

Noun

Specialty Definitions: Sepsis

Specialty Definition: Sepsis

Synonyms within Context: Sepsis

Disease

Crosswords: Sepsis

Commercial Usage: Sepsis

Books

Non-Fiction Usage: Sepsis

Usage Frequency: Sepsis

Expression: Sepsis

Frequency of Internet Keywords: Sepsis

Modern Translations: Sepsis

Albanian

Arabic

Bulgarian

Czech

Danish

Dutch

Finnish

French

German

Greek

Hebrew

Hungarian

Italian

Manx

Pig Latin

Portuguese

Russian

Serbo-Croatian

Spanish

Swedish

Thai

Turkish

Ukranian

Ancestral Language Translations: Sepsis

Derivations & Misspellings: Sepsis

Derivations

Misspellings

Rhyming with "Sepsis"

Anagrams: Sepsis

Scrabble® Enable2K-Verified Anagrams

Alternative Orthography: Sepsis

53 65 70 73 69 73

... . .--. ... .. ...

01010011 01100101 01110000 01110011 01101001 01110011

&#83 &#101 &#112 &#115 &#105 &#115

0053 0065 0070 0073 0069 0073

537182857585

INDEX