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Ribosome

Definition: Ribosome

Ribosome

Noun

1. Organelle in the cytoplasm of a living cell that is composed of ribonucleic acid; "the ribosome is the site of protein synthesis".

Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved.
 

Date "ribosome" was first used in popular English literature: sometime before 1985. (references)


Specialty Definitions: Ribosome

DomainDefinitions

Medicine

A granule of protein and RNA, synthesized in the nucleolus and found in the cytoplasm of cells. Ribosomes are the main sites of protein synthesis. Messenger RNA attaches to them and there receives molecules of transfer RNA bearing amino acids. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Specialty Definition: Ribosome

(From Wikipedia, the free Encyclopedia)

A ribosome is a complex of RNA and proteins that can translate mRNA into a polypeptide chain (e.g., a protein). They can be thought of as a factory that builds a protein from a set of genetic instructions. Ribosomes are found in the cytosol (the internal fluid of the cell) of all cells. . Ribosomes consist of two subunits (Fig. 1) that fit together (Fig. 2) and work as one to translate the mRNA into a polypeptide chain (Fig.3). Each subunit consists of one or two very large RNA molecules (known as ribosomal RNA or rRNA) and several smaller protein molecules.


Figure 1 : The subunits of a ribosome. Side and front view.
(A) Small subunit. (B) Large subunit. (1) Head. (2) Platform. (3) Base. (4) Ridge. (5) Central protuberance. (6) Back. (7) Stalk. (8) Front.

Free ribosomes occur in all cells, and also in mitochondria and chloroplasts in eukaryotic cells. Several free ribosomes can associate on a single mRNA molecule to form a polyribosome or polysome. Free ribosomes usually produce proteins that are used in the cytosol or in the organelle they occur in. When certain proteins are synthesized by a ribosome, it can become "membrane-bound", associated with the membrane of the nucleus and the rough endoplasmic reticulum (in eukaryotes only) for the time of synthesis. They insert the freshly produced polypeptide chains directly into the ER, from where they are transported to their destinations. Bound ribosomes usually produce proteins that are used within the cell membrane or are expelled from the cell via exocytosis.


Figure 2 : Large (1) and small (2) subunit fit together.

The ribosomal subunits of prokaryotes and eukaryotes are quite similar. However, prokaryotes use 70S ribosomes, each consisting of a (small) 30S and a (large) 50S subunit, whereas eukaryotes use 80S ribosomes, each consisting of a (small) 40S and a (large) 60S subunit.[The unit S means Svedberg units, a measure of the rate of sedimentation of a particle in a centrifuge, where the sedimentation rate is associated with the size of the particle. Svedberg units are not additive - two subunits together can have Svedberg values that do not add up to that of the entire ribosome.]


Figure 3 : Translation (1) of mRNA by a ribosome (2) into a polypeptide chain (3).
The mRNA begins with a start codon (AUG) and ends with a stop codon (UAG). Both ribosomal subunits (small and large) assemble at the start codon (the 5' end of the mRNA). The ribosome uses tRNA[transfer RNAs are RNA molecules that carry an amino acid and present the matching codon, according to the genetic code, to the ribosome.] which matches the current triplet on the mRNA to append an amino acid to the polypeptide chain. This is done for each triplet on the mRNA, while the ribosome moves towards the 3' end of the mRNA. Usually, several ribosomes are working parallel on a single mRNA.

The structure and function of ribosomes, and their attendant molecules, known as the translational apparatus, has been of ongoing research interest since the mid 20th century on through the early 21st century.

A triennial conference is held to discuss the ribosome. In 1999, the conference was held in Helsingoer, Denmark. The 2002 conference was held in Queenstown, New Zealand [1].

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Ribosome."

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Crosswords: Ribosome

English words defined with "ribosome": messenger RNA, mRNAtransfer DNA, translation, tRNA. (references)
Specialty definitions using "ribosome": 5' Untranslated Regionsaminoacyl-tRNA, Anisomycin, Anticodon, Arenaviridaeelongation factorGTP PyrophosphokinaseN-FormylmethioninePeptide Elongation Factor 1, Peptide Elongation Factor Tu, Peptide Termination FactorsRibosomal RNA, RNA, Transfer, Amino Acid-Specific, rRNASignal Recognition ParticleToyocamycin. (references)

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Commercial Usage: Ribosome

DomainTitle

Books

  • Control of Ribosome Synthesis: Proceedings of the Alfred Benzon Symposium IX Held at the Premises of the World Health Organization, Regional Office f (reference)

  • Ribosome Structure and Protein Biosynthesis (Structural Biology Series) (reference)

  • The Eukaryotic Ribosome (reference)

  • The Ribosome (Cold Spring Harbor Symposia on Quantitative Biology, Vol. 66) (reference)

    (more book examples)

Source: compiled by the editor from various references; see credits.

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Photo Album: Ribosome

ThumbnailDescription & Credit

Illustration of structure of hyphal tip. er - endoplasmic reticulum, s - septum, m - mitochondrion, n - nucleus, vgs - Golgi, r - ribosome, p - plasma membrane, v - vesicles.Credit: CDC.

Source: compiled by the editor from various references; see credits.

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Usage Frequency: Ribosome

"Ribosome" is generally used as an adjective (general or positive) -- approximately 100.00% of the time. "Ribosome" is used about 19 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted)
Parts of SpeechPercentUsage per
100 Million Words
Rank in English
Adjective (general or positive)100%1980,337

Source: compiled by the editor from several corpora; see credits.

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Frequency of Internet Keywords: Ribosome

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

  the ribosome

35

  animation ribosome

6

  function ribosome

2

  binding ribosome site

2

  movie ribosome

2
Source: compiled by the editor from various references; see credits.

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Modern Translations: Ribosome

Language Translations for "ribosome"; alternative meanings/domain in parentheses.

Chinese 

  

核糖体. (various references)

   

Danish

  

ribosom. (various references)

   

Dutch

  

ribosoom. (various references)

   

Finnish

  

ribosomi. (various references)

   

French

  

ribosome. (various references)

   

German

  

Ribosom. (various references)

   

Greek 

  

ριβόσωμα. (various references)

   

Italian

  

ribosoma. (various references)

   

Japanese Kanji 

  

リベット接合 (determination of a loser to win the next time, liberal, liberalism, liberalist, Liberia, repair, revenge, revolver, revolving, revolving loan, revolvingsystem, rivet connection), ライフル銃 (Leipzig, librarian, library, life-work, lilac, lime, limelight, live, live house, live recording, live show, rhyme, rifle). (various references)

   

Japanese Katakana 

  

リボゾーム , リボソーム , ライボゾーム . (various references)

   

Korean 

  

리보솜. (various references)

   

Pig Latin

  

ibosomeray

   

Portuguese

  

ribossoma. (various references)

   

Spanish

  

ribosoma. (various references)

   

Swedish

  

ribosom. (various references)

Source: compiled by the editor from various translation references.

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Derivations & Misspellings: Ribosome

Derivations

Words beginning with "ribosome": ribosomes. (additional references)

Words ending with "ribosome": polyribosome. (additional references)

Words containing "ribosome": polyribosomes. (additional references)


Misspellings

"Ribosome" is suggested in spellcheckers for the following: Eriosoma, rhibosome, ribosie, riboso, ribosomer, ribosomes, ribozyme, ribozymes, ricos-omes, rimosum, Rubusana. (additional references)

Source: compiled by the editor, based on several corpora (additional references).

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Anagrams: Ribosome

Scrabble® Enable2K-Verified Anagrams

Words within the letters "b-e-i-m-o-o-r-s"

-1 letter: boomers, boomier, roomies.

-2 letters: biomes, boomer, bromes, bromos, brooms, isomer, moires, morose, ombers, ombres, ribose, rimose, romeos, roomie, somber, sombre.

-3 letters: berms, besom, biers, biome, birse, booms, boors, bores, bosom, bries, brims, brios, brome, bromo, broom, broos, brose, emirs, mires, miser, moire, moors, moose, mores, morse, oboes, omber, ombre, omers, oorie, osier, ribes.

 Words containing the letters "b-e-i-m-o-o-r-s"
 

+1 letter: broomiest, ribosomes.

 

+2 letters: bloomeries, boosterism, bottomries, motorbikes.

 

+3 letters: biopolymers, boosterisms, bridegrooms, coxcombries, microprobes, mobocracies, rhomboideus, snowmobiler.

 

+4 letters: aeroembolism, embrocations, embryologies, embryologist, polyribosome, snowmobilers, theobromines.

 

+5 letters: aeroembolisms, embryologists, immunosorbent, myelofibroses, myelofibrosis, neurofibromas, overambitious, polyribosomes, postembryonic, precombustion, thrombokinase, timberdoodles.

Source: compiled by the editor from various references; see credits.

SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.

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Alternative Orthography: Ribosome


Hexadecimal (or equivalents, 770AD-1900s) (references)

52 69 62 6F 73 6F 6D 65

Leonardo da Vinci (1452-1519; backwards) (references)

American Sign Language (origins from 1620-1817 in Italy and, especially, France) (references)

=

Semaphore (1791, in France) (references)

Braille (1829, in France) (references)

Morse Code (1836) (references)

.-.    ..    -...    ---    ...    ---    --    .

Dancing Men (Sir Arthur Conan Doyle, 1903) (references)

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Bibliographic Items: "ribosome"


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Amazon.com BOOKS: Search for: "ribosome"

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Public Service or Web Sites Triggered by: Ribosome