Copyright © Philip M. Parker, INSEAD. Terms of Use.
Definition: Protease |
ProteaseNoun1. Any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis. Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved. |
| Domain | Definition |
Health | Proteinase (= any enzyme that catalyses the splitting of interior peptide bonds in a protein). (references) |
| Any enzyme that catalyzes hydrolysis of a protein. (references) | |
Medicine | Protease:any enzyme that catalyzes hydrolysis of a protein. Source: European Union. (references) |
Source: compiled by the editor from various references; see credits. | |
(From Wikipedia, the free Encyclopedia)
Peptidases (old term: proteases, pronounced pro-tea-aces) are enzymes which break peptide bonds of proteins. They use a molecule of water to do so and are thus classified as hydrolases.
Peptidases occur naturally in living organisms, where they are used for molecular digestion and the breakdown of unwanted proteins. Peptidases can break either specific peptide bonds (limited proteolysis), depending on the amino acid sequence of a protein, or break down a complete peptide to amino acids (unlimited proteolysis).
Some viruseses, with HIV among them, depend on proteases in their reproductive cycle. Thus, protease inhibitors are developed as antiviral means.
Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Peptidase."
| The following table is compiled from various sources, across various languages. When English abbreviations or acronyms come from a non-English source, this is noted. | |||
| Entry | Source | Expression | Field |
| PrP | English | Protease resistant protein | Medicine |
Source: compiled by the editor, based on several corpora (additional references). | |||
Synonyms: ProteaseSynonyms: peptidase (n), proteinase (n), proteolytic enzyme (n). (additional references) |
Crosswords: Protease |
| English words defined with "protease": plasminogen activator ♦ urokinase. (references) |
| Specialty definitions using "protease": ABT-378, ag1343, alpha 1-Antitrypsin, aminoethyl, aminoethyl-benzenesulfonylfluoride, Antigens, CD26, Antipain, Antiretroviral Therapy, Highly Active ♦ beta-site-APP-clearing enzyme ♦ Combination Therapy, Complement 3c ♦ Gene Products, env, Gene Products, pol, Genes, pol ♦ HIV Protease, HIV Protease Inhibitors ♦ Indinavir ♦ Kaletra ♦ Leupeptins, lopinavir ♦ Nelfinavir, nelfinavir mesylate ♦ Pancreatic Elastase, Peptide Mapping, protease inhibitor, Protein Footprinting ♦ Ritonavir ♦ Saquinavir, saquinavir mesylate ♦ tick anticoagulant peptide, triple combination, triple-drug therapy ♦ Viracept. (references) |
| Non-English Usage: "Protease" is also a word in the following languages with English translations in parentheses. Danish (protease), Dutch (protease), German (protease), Portuguese (protease, proteinase, proteolytic enzyme). |
| Domain | Title | ||
Books |
| ||
Periodicals |
| ||
Source: compiled by the editor from various references; see credits. | |||
| Subject | Topic | Quote |
Health | High levels of the protease cathepsin D are associated with an unfavorable prognosis. (references) | |
People who take the protease inhibitor indinavir, a drug used to treat HIV infection and AIDS, are at risk of developing kidney stones. (references) | ||
Measurement of the activity of palmitoyl-protein thioesterase involved in CLN1 and the acid protease involved in CLN2 in white blood cells or cultured skin fibroblasts can be used to confirm these diagnoses. (references) | ||
Source: compiled by the editor from ICON Group International, Inc.; see credits. | ||
| "Protease" is generally used as a noun (singular) -- approximately 94.44% of the time. "Protease" is used about 18 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted) |
| Parts of Speech | Percent | Usage per 100 Million Words | Rank in English |
| Noun (singular) | 94.44% | 17 | 85,106 |
| Lexical Verb (base form) | 5.56% | 1 | 339,140 |
| Total | 100.00% | 18 | N/A |
Source: compiled by the editor from several corpora; see credits.
Expressions using "protease": 3C protease ♦ bacterial protease ♦ HIV Protease ♦ HIV Protease Inhibitors ♦ protease inhibitor ♦ Protease Inhibitors. Additional references. | |
| Hyphenated Usage | |
Beginning with "protease": protease-resistant. | |
| Source: compiled by the editor from various references; see credits. | |
| The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com. |
| Language | Translations for "protease"; alternative meanings/domain in parentheses. | |
Chinese | 蛋白酶 (proteases, proteinase). (various references) | |
Danish | protease (proteinase, proteolytic enzyme). (various references) | |
Dutch | protease (proteinase, proteolytic enzyme). (various references) | |
Finnish | proteaasi (proteinase, proteolytic enzyme). (various references) | |
French | protéase (proteinase, proteolytic enzyme). (various references) | |
German | Protease (proteinase, proteolytic enzyme). (various references) | |
Greek | πρωτεάση (endopeptidase, proteinase, proteolytic enzyme), πρωτεολυτικό ένζυμο (proteinase, proteolytic enzyme). (various references) | |
Italian | proteasi (proteinase, proteolytic enzyme). (various references) | |
Korean | "로테아 (proteases). (various references) | |
Pig Latin | oteasepray.(various references) | |
Portuguese | protease (proteinase, proteolytic enzyme), protéase. (various references) | |
Spanish | proteasa (proteinase, proteolytic enzyme). (various references) | |
Swedish | proteas (proteinase, proteolytic enzyme), peptidas (proteinase, proteolytic enzyme). (various references) | |
| Source: compiled by the editor from various translation references. | ||
Derivations | |
Words beginning with "protease": proteases. (additional references) | |
| |
"Protease" is suggested in spellcheckers for the following: Portessie, Portuense, Potasse, Protasia, Protasov, Protea, Proteaceae, Proteas, prottas, protuse. (additional references) | |
| Source: compiled by the editor, based on several corpora (additional references). | |
Scrabble® Enable2K-Verified Anagrams | |
Direct Anagrams: operates. | |
| Words within the letters "a-e-e-o-p-r-s-t" | |
-1 letter: esparto, operate, proteas, repeats, retapes, roseate, seaport. | |
-2 letters: aretes, easter, eaters, etapes, oaters, operas, orates, pareos, paster, pastor, paters, peseta, pester, peters, poster, prates, preset, presto, protea, repast, repeat, repose, repots, reseat, respot, retape, sapote, seater, serape, soaper, stereo, stoper, tapers, teaser, topees, topers, trapes, tropes. | |
-3 letters: apers, aport, apres, apter, arete, arose. | |
| Words containing the letters "a-e-e-o-p-r-s-t" | |
+1 letter: ephorates, operettas, periostea, perorates, personate, poetaster, proteases. | |
+2 letters: atmosphere, azeotropes, cooperates, evaporates, evaporites, notepapers, operatives, peashooter, perborates, percolates, perforates, periosteal, personated, personates, poetasters, porterages, prestorage, procreates, proteinase, reoperates, reportages, reprobates, tetraspore, treponemas. | |
+3 letters: atmosphered, atmospheres, depredators, desperation, houseparent, impersonate, metanephros, outpreaches, paternoster, patronesses, peashooters, pejoratives, pentamerous, perestroika, permeations, personative, prestorages, proteinases, repopulates, spirochaete, stereograph, temporaries, tetraspores, transportee, waterpowers. | |
| Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro. | |
| 1. Definition 2. Synonyms 3. Crosswords 4. Usage: Commercial | 5. Quotations: Non-fiction 6. Usage Frequency 7. Expressions 8. Expressions: Internet | 9. Translations: Modern 10. Abbreviations 11. Acronyms 12. Derivations | 13. Anagrams 14. Bibliography |
Copyright © Philip M. Parker, INSEAD. Terms of Use.
