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OPTIC NEURITIS

Specialty Definition: OPTIC NEURITIS

DomainDefinition

Health

Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as multiple sclerosis, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis). (references)

Medicine

Inflammation of the optic nerve that occurs in two principal forms, intraocular optic neuritis and retrobulbar optic neuritis. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Specialty Definition: Optic neuritis

(From Wikipedia, the free Encyclopedia)

Optic neuritis is the inflammation of the optic nerve that may cause a complete or partial loss of vision. The optic nerve comprises axons that emerge from the retina of the eye and carry visual information to the occipital cortex of the brain to be processed into vision. Inflammation of the optic nerve causes loss of vision usually due to the swelling and destruction of the myelin sheath covering the optic nerve. Direct axonal damage may also play a role in nerve destruction in many cases. The major causes are viral-bacterial infections (e.g. herpes zoster), autoimmune disorders (e.g. lupus) and the inflammation of vessels (vasculitis) nourishing the optic nerve. Optic neuritis can also emerge as an attendant, first, or sole manifestation of multiple sclerosis.

Major symptoms are sudden loss of vision (partial or complete) and occasionally pain on movement of the eyes. Some patients with optic neuritis may lose their color vision, as well. On medical examination the head of the bulging optic nerve can easily be visualised by an ophthalmoscope. In many cases, only one eye is affected and patients may not be aware of the loss of color vision until the doctor asks them to close or cover the healthy eye.

In most cases, visual functions return to normal within a few weeks, but they may also advance to a complete and permanent state of visual loss. Therefore, systemic intravenous treatment with corticosteroids, which may quicken the healing of the optic nerve, prevent complete loss of vision, and delay the onset of other multiple sclerosis symptoms, is strongly recommended. It has been demonstrated that oral administration of corticosteroids in this situation may result in an even worse outcome than that of the non-treated patients (though oral steroids are generally prescribed after the intravenous course, to wean the patient off the medication). This effect of corticosteroids seems to be limited to optic neuritis and has not been observed in other diseases treated with corticosteroids. Very occasionally, the sheath around the optic nerve may be cut off to decrease the pressure and thus increase the pace of healing.

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Optic neuritis."

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Crosswords: OPTIC NEURITIS

Specialty definitions using "OPTIC NEURITIS": neuritis of the optic nerve. (references)

Source: compiled by the editor from various references; see credits.

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Commercial Usage: OPTIC NEURITIS

DomainTitle

Books

Source: compiled by the editor from various references; see credits.

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Non-Fiction Usage: OPTIC NEURITIS

SubjectTopicQuote

Health

This has led to general recognition of optic neuritis as an early sign of MS, especially if tests also reveal abnormalities in the patient's spinal fluid. (references)

Fifty-five percent of MS patients will have an attack of optic neuritis at some time or other and it will be the first symptom of MS in approximately 15 percent. (references)

Extremely variable, including granulomatous hepatitis, peripheral arthritis, spondylitis, anemia, leukopenia, thrombocytopenia, meningitis, uveitis, optic neuritis, papilledema, and endocarditis. (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Frequency of Internet Keywords: OPTIC NEURITIS

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

optic neuritis

198

optic neuritis cause

5

optic neuritis and multiple sclerosis

2
Source: compiled by the editor from various references; see credits.

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Modern Translation: OPTIC NEURITIS

Language Translations for "OPTIC NEURITIS"; alternative meanings/domain in parentheses.

Danish

  

opticusneurit (neuritis of the optic nerve), retrobulbær neurit (retrobulbarneuritis), neuropapillitis (neuropapillitis), neuritis optica intraocularis (neuropapillitis), neuritis descendens (retrobulbarneuritis). (various references)

   

Dutch

  

neuropapillitis (neuritis of the optic nerve, neuropapillitis), neuritis optica (neuritis of the optic nerve, neuropapillitis), neuritis descendens (retrobulbarneuritis). (various references)

   

French

  

neuropapillite, névrite optique (neuritis of the optic nerve), névrite descendante. (various references)

   

German

  

Optikusneuritis (neuritis of the optic nerve), Papillitis (papillitis), Neuropapillitis optica (neuropapillitis), Neuritis optica s.nervi optici (neuritis of the optic nerve), Neuritis optica intraocularis (neuropapillitis), Neuritis descendens (retrobulbarneuritis). (various references)

   

Greek 

  

οπτική νευρίτιδα (neuritis of the optic nerve). (various references)

   

Italian

  

papillite (papillitis), nevrite retrobulbare (retrobulbarneuritis), nevrite ottica orbitale (retrobulbarneuritis), nevrite ottica (neuritis of the optic nerve), nevrite intraoculare (neuropapillitis), neuropapillite (neuropapillitis). (various references)

   

Pig Latin

  

opticay euritisnay

   

Portuguese

  

nevrite óptica (neuritis of the optic nerve). (various references)

   

Spanish

  

neuropapilitis (neuropapillitis), neuritis óptica (neuritis of the optic nerve, retrobulbarneuritis). (various references)

Source: compiled by the editor from various translation references.

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Anagrams: OPTIC NEURITIS

Scrabble® Enable2K-Verified Anagrams

Words within the letters "c-e-i-i-i-n-o-p-r-s-t-t-u"

-2 letters: peritonitis.

-3 letters: introspect, isentropic, nepotistic, pernicious, prosciutti, supertonic, tonicities, tricotines, trisection, triunities.

-4 letters: cornetist, countries, cretinous, croupiest, eroticist, eruptions, inceptors, inspector, intercuts, neuritics, neurotics, outpities, outprices, outsprint, petitions, pietistic, pointiest, precision, printouts, proustite, retinitis, tinctures, toreutics, touristic, tricotine, trinities, tropistic, utopistic.

-5 letters: centrist, citreous, citrines, citterns, coinsure, cointers, conspire, construe, contrite, corniest, cottiers, counters.

 Words containing the letters "c-e-i-i-i-n-o-p-r-s-t-t-u"
 

+5 letters: immunoprecipitates, incorruptibilities.

Source: compiled by the editor from various references; see credits.

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INDEX

1. Crosswords
2. Usage: Commercial
3. Quotations: Non-fiction
4. Expressions: Internet
5. Translations: Modern
6. Anagrams
7. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.