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Norepinephrine

Definition: Norepinephrine

Norepinephrine

Noun

1. A catecholamine precursor of epinephrine that is secreted by the adrenal medulla and also released at synapses.

Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved.
 

Specialty Definitions: Norepinephrine

DomainDefinitions

Health

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic. (references)

Medicine

Norepinephrine. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Specialty Definition: Norepinephrine

(From Wikipedia, the free Encyclopedia)

The chemical compound norepinephrine, also known as noradrenaline NC8O3H11 is a catecholamine neurotransmitter hormone released from the adrenal glands that affects parts of the human brain where attention and impulsivity are controlled. This compound is part of the fight-or-flight response and also directly increases heart rate, energy release from fat, and muscle readiness.

The host of physiological changes activated by a stressful event are unleashed in part by activation of a nucleus in the brain stem called the locus ceruleus. This nucleus is the origin of most norepinephrine pathways in the brain. Neurons using norepinephrine as their neurotransmitter project bilaterally from the locus ceruleus along distinct pathways to the cerebral cortex, limbic system, and the spinal cord, among other projections.

Normally, when someone is in a serene, unstimulated state, the "firing" of neurons in the locus ceruleus is minimal. A novel stimulus, once perceived, is relayed from the sensory cortex of the brain through the thalamus to the brain stem. That route of signaling increases the rate of noradrenergic activity in the locus ceruleus, and the person becomes alert and attentive to the environment. If the stimulus is perceived as a threat, a more intense and prolonged discharge of the locus ceruleus activates the sympathetic division of the autonomic nervous system (Thase & Howland, 1995). The activation of the sympathetic nervous system leads to the release of norepinephrine from nerve endings acting on the heart, blood vessels, respiratory centers, and other sites. The ensuing physiological changes constitute a major part of the acute stress response. The other major player in the acute stress response is the hypothalamic-pituitary-adrenal axis.

External links:

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Norepinephrine."

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Synonym: Norepinephrine

Synonym: noradrenaline (n). (additional references)

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Crosswords: Norepinephrine

English words defined with "norepinephrine": catecholamineEdronaxMAO, monoamine oxidaseneurohormonereboxetinetricyclic, tricyclic antidepressant, tricyclic antidepressant drugvasoconstrictive, vasoconstrictor. (references)
Specialty definitions using "norepinephrine": 1-Methyl-4-phenylpyridinium3-Methoxy-4-hydroxyphenylethanolAdrenergic Antagonists, Amoxapine, Antidepressive Agents, TricyclicBiogenic Amine NeurotransmittersChromaffin GranulesDesipramineFusaric AcidGuanethidineMetaraminol, MethoxyhydroxyphenylglycolNordefrin, NormetanephrinePhenylethanolamine N-MethyltransferaseReceptors, Adrenergic, beta-1, Receptors, Adrenergic, beta-2, Receptors, Biogenic Amine, Receptors, CatecholamineSibutramine, Sympathetic Fibers, Postganglionic, Sympatholytics. (references)

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Commercial Usage: Norepinephrine

DomainTitle

Books

  • Norepinephrine (reference)

  • Norepinephrine (Frontiers of Clinical Neuroscience, Vol 2) (reference)

    (more book examples)

Source: compiled by the editor from various references; see credits.

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Non-Fiction Usage: Norepinephrine

SubjectTopicQuote

Health

Norepinephrine and serotonin, inhibitory chemicals that help the brain regulate acetylcholine. (references)

Other hormones that influence blood sugar levels are cortisol, growth hormone, and catecholamines (epinephrine and norepinephrine). (references)

The brain may signal the release of painkillers found in the spinal cord, including serotonin, norepinephrine, and opioid-like chemicals. (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Frequency of Internet Keywords: Norepinephrine

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

  norepinephrine

170

  inhibitor norepinephrine reuptake

10

  depression norepinephrine

7

  iv norepinephrine

7

  norepinephrine serotonin

7

  inhibitor norepinephrine reuptake selective

6

  inhibitor norepinephrine reuptake serotonin

4

  epinephrine norepinephrine

2

  anxiety norepinephrine

2

  dopamine norepinephrine

2

  norepinephrine reuptake

2
Source: compiled by the editor from various references; see credits.

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Modern Translations: Norepinephrine

Language Translations for "norepinephrine"; alternative meanings/domain in parentheses.

Chinese 

  

降肾上腺 . (various references)

   

Danish

  

norepinephrin. (various references)

   

Dutch

  

norepinephrine, norepinefrine, noradrenaline (noradrenaline). (various references)

   

Finnish

  

norepinefriini. (various references)

   

French

  

norépinéphrine. (various references)

   

German

  

Norepinephrin. (various references)

   

Italian

  

norepinefrina. (various references)

   

Pig Latin

  

orepinephrinenay

   

Portuguese

  

norepinefrina. (various references)

   

Spanish

  

norepinefrina. (various references)

   

Swedish

  

norepinefrin. (various references)

Source: compiled by the editor from various translation references.

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Derivations: Norepinephrine

Derivations

Words beginning with "norepinephrine": norepinephrines. (additional references)

Source: compiled by the editor, based on several corpora (additional references).

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Anagrams: Norepinephrine

Scrabble® Enable2K-Verified Anagrams

Words within the letters "e-e-e-h-i-i-n-n-n-o-p-p-r-r"

-3 letters: epinephrine.

-4 letters: epinephrin.

 Words containing the letters "e-e-e-h-i-i-n-n-n-o-p-p-r-r"
 

+1 letter: norepinephrines.

Source: compiled by the editor from various references; see credits.

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Alternative Orthography: Norepinephrine


Hexadecimal (or equivalents, 770AD-1900s) (references)

4E 6F 72 65 70 69 6E 65 70 68 72 69 6E 65

Leonardo da Vinci (1452-1519; backwards) (references)

American Sign Language (origins from 1620-1817 in Italy and, especially, France) (references)

=

Semaphore (1791, in France) (references)

Braille (1829, in France) (references)

Morse Code (1836) (references)

-.    ---    .-.    .    .--.    ..    -.    .    .--.    ....    .-.    ..    -.    .

Dancing Men (Sir Arthur Conan Doyle, 1903) (references)

Binary Code (1918-1938, probably earlier) (references)

01001110 01101111 01110010 01100101 01110000 01101001 01101110 01100101 01110000 01101000 01110010 01101001 01101110 01100101

HTML Code (1990) (references)

&#78 &#111 &#114 &#101 &#112 &#105 &#110 &#101 &#112 &#104 &#114 &#105 &#110 &#101

ISO 10646 (1991-1993) (references)

004E 006F 0072 0065 0070 0069 006E 0065 0070 0068 0072 0069 006E 0065

British Sign Language (Fingerspelling, BSL; 1992, British Deaf Association Dictionary of British Sign Language) (references)

Encryption (beginner's substitution cypher): (references)

4881847182758071827484758071

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INDEX

1. Definition
2. Synonyms
3. Crosswords
4. Usage: Commercial
5. Quotations: Non-fiction
6. Expressions: Internet
7. Translations: Modern
8. Derivations
9. Anagrams
10. Orthography
11. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.