NEPRILYSIN

Domain	Definition
Health	Enzyme that is a major constituent of kidney brush-border membranes and is also present to a lesser degree in the brain and other tissues. It preferentially catalyzes cleavage at the amino group of hydrophobic residues of the B-chain of insulin as well as opioid peptides and other biologically active peptides. The enzyme is inhibited primarily by EDTA, phosphoramidon, and thiorphan and is reactivated by zinc. Neprilysin is identical to common acute lymphoblastic leukemia antigen (CALLA), an important marker in the diagnosis of human acute lymphocytic leukemia. EC 3.4.24.11. (references)
Source: compiled by the editor from various references; see credits.

Frequency of Internet Keywords: NEPRILYSIN

Anagrams: NEPRILYSIN

Scrabble® Enable2K-Verified Anagrams
	Words within the letters "e-i-i-l-n-n-p-r-s-y"
	-2 letters: spinnery.
	-3 letters: inliers, innerly, inspire, pilsner, pinners, pinnies, spinier, spinner, spinney, splenii.
	-4 letters: inlier, inners, linens, lineny, liners, linier, linins, linsey, lipins, lisper, lysine, pennis, pensil, perils, pinery, pinier, pinner, pinyin, pliers, plyers, renins, repins, resiny, ripely, ripens, sileni, sinner, sniper, spinel, spinny, spline.
	-5 letters: inner, lenis, liens, liers, linen, liner, lines, liney, linin.
	Words containing the letters "e-i-i-l-n-n-p-r-s-y"
	+4 letters: nortriptylines.
	+5 letters: hyperinflations, hyperinsulinism.
Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.