Copyright © Philip M. Parker, INSEAD. Terms of Use.
Definition: Naloxone |
NaloxoneNoun1. A potent narcotic antagonist (trade name Narcan) especially effective with morphine. Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved. |
| Domain | Definitions |
Health | A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors. (references) |
Medicine | Endorphin blocker. Source: European Union. (references) |
Source: compiled by the editor from various references; see credits. | |
(From Wikipedia, the free Encyclopedia)
The drug has an extremely high affinity for the opiate receptors on nerve cells in the brain, and blocks those receptors quickly, often throwing addicts into immediate withdrawal symptoms.
Naloxone is injected, usually initially intravenously for fastest action. The drug acts after about two minutes, and its effects may last about 45 minutes.
Naloxone has been distributed as part of emergency kits to heroine addicts, which has been shown to reduce death rates.
The drug also blocks the action of pain-lowering endorphins which the body produces naturally. The likely reason for this is that these endorphins operate on the same opiate receptors. In one experiment, women treated with naloxone reported higher pain levels during childbirth than women not so treated; in another experiment, the pain lowering effect of placebos was blocked if the placebos were administered along with naloxone.
The patent for the drug has expired and naloxone is manufactured by various companies.
Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Naloxone."
Synonym: NaloxoneSynonym: Narcan (n). (additional references) |
Crosswords: Naloxone |
| Specialty definitions using "naloxone": beta-Endorphin ♦ Diprenorphine ♦ FK 33-824. (references) |
| Domain | Title |
Books | |
Source: compiled by the editor from various references; see credits. | |
| Subject | Topic | Quote |
Health | Finally, naloxone, which counteracts the effects of opioids, is used to treat overdoses. (references) | |
Naloxone and naltrexone are medications that also block the effects of morphine, heroin, and other opiates. (references) | ||
That opioid antagonists such as naloxone reverse the analgesic effects of acupuncture further strengthens this hypothesis. (references) | ||
Source: compiled by the editor from ICON Group International, Inc.; see credits. | ||
| "Naloxone" is generally used as a noun (singular) -- approximately 80.00% of the time. "Naloxone" is used about 5 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted) |
| Parts of Speech | Percent | Usage per 100 Million Words | Rank in English |
| Noun (singular) | 80% | 4 | 175,879 |
| Lexical Verb (base form) | 20% | 1 | 339,140 |
| Total | 100.00% | 5 | N/A |
Source: compiled by the editor from several corpora; see credits.
| The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com. |
| Expression | Frequency per Day |
naloxone | 54 |
pentazocine naloxone | 8 |
hydrochloride naloxone | 2 |
buprenorphine naloxone | 2 |
naloxone hcl | 2 |
| Source: compiled by the editor from various references; see credits. | |
| Language | Translations for "naloxone"; alternative meanings/domain in parentheses. | |
Danish | naloxon. (various references) | |
Dutch | naloxone, naloxon. (various references) | |
Finnish | naloksoni. (various references) | |
French | naloxone, naloxon. (various references) | |
German | Naloxon. (various references) | |
Greek | ναλοξόνη. (various references) | |
Italian | naloxone, nalossone, nalassone. (various references) | |
Pig Latin | aloxonenay.(various references) | |
Portuguese | naloxona. (various references) | |
Spanish | naloxone, naloxona. (various references) | |
Swedish | naloxon. (various references) | |
| Source: compiled by the editor from various translation references. | ||
Derivations | |
Words beginning with "naloxone": naloxones. (additional references) | |
| Source: compiled by the editor, based on several corpora (additional references). | |
Scrabble® Enable2K-Verified Anagrams | |
| Words within the letters "a-e-l-n-n-o-o-x" | |
-3 letters: alone, annex, anole, axone, xenon. | |
-4 letters: aeon, aloe, anon, axel, axle, axon, elan, enol, exon, lane, lean, leno, loan, lone, loon, neon, noel, nolo, nona, none, noon, olea, oleo, oxen. | |
-5 letters: ale, ane, axe, eon, lax, lea, lex, loo, lox, nae, nan, noo, ole, one, oxo. | |
| Words containing the letters "a-e-l-n-n-o-o-x" | |
+1 letter: naloxones. | |
+5 letters: cyclohexanone, nonhomosexual. | |
| Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro. | |
Hexadecimal (or equivalents, 770AD-1900s) (references)4E 61 6C 6F 78 6F 6E 65 |
| Leonardo da Vinci (1452-1519; backwards) (references)
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| American Sign Language (origins from 1620-1817 in Italy and, especially, France) (references)
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| Semaphore (1791, in France) (references)
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| Braille (1829, in France) (references)
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Morse Code (1836) (references)-. .- .-.. --- -..- --- -. . |
| Dancing Men (Sir Arthur Conan Doyle, 1903) (references)
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Binary Code (1918-1938, probably earlier) (references)01001110 01100001 01101100 01101111 01111000 01101111 01101110 01100101 |
HTML Code (1990) (references)N a l o x o n e |
ISO 10646 (1991-1993) (references)004E 0061 006C 006F 0078 006F 006E 0065 |
| British Sign Language (Fingerspelling, BSL; 1992, British Deaf Association Dictionary of British Sign Language) (references)
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Encryption (beginner's substitution cypher): (references)4867788190818071 |
| 1. Definition 2. Synonyms 3. Crosswords 4. Usage: Commercial | 5. Quotations: Non-fiction 6. Usage Frequency 7. Expressions: Internet 8. Translations: Modern | 9. Derivations 10. Anagrams 11. Orthography 12. Bibliography |
Copyright © Philip M. Parker, INSEAD. Terms of Use.
