MICE, SCID

Domain	Definition
Health	Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice. (references)
Source: compiled by the editor from various references; see credits.

Anagrams: MICE, SCID

Scrabble® Enable2K-Verified Anagrams
	Words within the letters ",-c-c-d-e-i-i-m-s"
	-2 letters: cimices.
	-3 letters: imides, medics, sicced.
	-4 letters: cedis, deism, dices, dimes, disci, disme, imide, imids, medic, medii, mesic, midis.
	-5 letters: cedi, dice, dies, dime, dims, disc, emic, iced, ices, idem, ides, imid, mice, midi, mids, mise, semi, sice, side.
Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.