MICE, INBRED CFTR

Domain	Definition
Health	A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands. (references)
Source: compiled by the editor from various references; see credits.

Anagrams: MICE, INBRED CFTR

Scrabble® Enable2K-Verified Anagrams
	Words within the letters ",-b-c-c-d-e-e-f-i-i-m-n-r-r-t"
	-5 letters: dentifrice, directrice, interfiber, tenebrific.
Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.