Copyright © Philip M. Parker, INSEAD. Terms of Use.
Definition: Metastatic |
MetastaticAdjective1. Relating to or affected by metastasis; "metastatic growth". Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved. |
Date "metastatic" was first used in popular English literature: sometime before 1900. (references) |
| Domain | Definitions |
Health | Having to do with metastasis, which is the spread of cancer from one part of the body to another. (references) |
Source: compiled by the editor from various references; see credits. | |
Crosswords: Metastatic |
| English words defined with "metastatic": metastatic tumor. (references) |
| Specialty definitions using "metastatic": Bone Marrow Neoplasms, Brain Neoplasms ♦ Endocarditis, Subacute Bacterial, Epidural Neoplasms ♦ Gold Colloid, Radioactive, Goserelin ♦ Lymphoma, Large-Cell, Ki-1 ♦ metastatic cancer, metastatic cell in circulation ♦ Nervous System Neoplasms ♦ secondary tumor ♦ Tissue Inhibitor-of Metalloproteinase-2. (references) |
| Domain | Title |
References | |
Books |
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Source: compiled by the editor from various references; see credits. | |
| Thumbnail | Description & Credit | Thumbnail | Description & Credit |
 | The patient is a 53 year old woman with metastatic melanoma to multiple subcutaneous sites and retroperitoneum. She was treated with tumor infiltrating lymphocytes (TILs) transduced with the gene for tumor necrosis factor (TNF). Pretreatment biopsy shows multiple live melanoma cells with little lymphoid infiltrate. Following treatment with TNF gene modified TILs plus interleukin-2, a biopsy of another lesion showed massive coagulative necrosis of the tumor with no viable tumor seen. This is a typical picture seen in experimental animals treated with tumor necrosis factor. This patient has had a substantial objective response that is currently ongoing at nine months following initiation of treatment. Credit: Unknown photographer/artist. |  | Human metastatic breast cancer in the lymph nodes. Stained by immunocytochemical for epithelial membrane antigen. Magnified to 400x. Credit: Unknown photographer/artist. |
 | This illustration with and without text, titled "How Cancer Spreads" explains the process of metastasis. Once metastatic cells are attached to the basement membrane (a physical barrier that seperates tissue components), they break through with the help of an enzyme called type IV collagenase. Cancer cells then move through the blood stream enabling them to spread to other parts of the body. A secondary tumor may form at another site in the body. See artwork: GA-17. Credit: Jane Hurd (artist). |  | The metastatic colony is the end result of a complicated multistep process. The tumor cells from a primary tumor invade local tissue and gain access to the venous circulation (intravasation). Circulating tumor cells, singly or in clumps, are transported to target organs where they lodge in the capillary bed. Thus arrested, these tumor cells penetrate the endothelial cell lining and the underlining basement membrane to exit the circulation (extravasation). They then grow as a metastatic colony, a development that requires new blood vessels (neovascularization). To complete this multistep process, the tumor cells must overcome the host's defenses. Credit: Unknown photographer/artist. |
 | This is advanced malignant melanoma. At the left, one can see a plaque of early, radial growth phase superficial spreading melanoma. To the right, and contiguous with the plaque, is a pink (amelanotic) nodule of deeply invasive vertical growth phase melanoma. Melanomas diagnosed at this stage have a poor prognosis; many of these patients develop metastatic disease and die from their cancer. In the majority of instances, the plaque stage of melanoma is present for a sufficient period of time to permit its diagnosis and removal before it progresses to a more advanced (and more difficult to treat) stage. Credit: Unknown photographer/artist. | ||
Source: pictures compiled by the editor from various references; see picture credits. | |||
| Subject | Topic | Quote |
Health | The accumulated damage yields a highly malignant, metastatic tumor. (references) | |
Cancer cells in the liver would be called metastatic melanoma, not liver cancer. (references) | ||
Radiation is recommended to palliate symptoms in patients with metastatic disease. (references) | ||
Source: compiled by the editor from ICON Group International, Inc.; see credits. | ||
| "Metastatic" is generally used as an adjective (general or positive) -- approximately 100.00% of the time. "Metastatic" is used about 50 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted) |
| Parts of Speech | Percent | Usage per 100 Million Words | Rank in English |
| Adjective (general or positive) | 100% | 50 | 48,117 |
Source: compiled by the editor from several corpora; see credits.
Expressions using "metastatic": metastatic cancer ♦ metastatic cell in circulation ♦ metastatic tumor. Additional references. | |
| Hypenated Usage | |
Ending with "metastatic": non-metastatic. | |
| Source: compiled by the editor from various references; see credits. | |
| The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com. |
| Language | Translations for "metastatic"; alternative meanings/domain in parentheses. | ||||||||||||||||
Danish | metastatisk kalcinose (metastatic calcinosis), metastatisk infarkt (metastatic infarct), metastatisk gigt (metastatic gout), metastatisk arthrit (metastatic arthritis), metastatisk absces (metastatic abscess), sekundær cancer (metastatic cancer, secondary cancer), embolisk encephalit (embolic metastatic encephalitis), disseminerede cancermetastaser (metastatic dissemination of cancers), akut metastasesyndrom (acute metastatic progression). (various references) | ||||||||||||||||
Dutch | metastatische calcinosis (metastatic calcinosis), metastatisch infarct (metastatic infarct), metastatisch absces (metastatic abscess), ziekte van Da Costa (metastatic gout), uitgezaaide metastasen (metastatic dissemination of cancers), secundaire kanker (metastatic cancer, secondary cancer), ingewandenjicht (metastatic gout), gedissemineerde metastasen (metastatic dissemination of cancers), arthritis infectiosa (metastatic arthritis), acute metastasering (acute metastatic progression). (various references) | ||||||||||||||||
Finnish | syöpäetäpesäkkeiden leviäminen (metastatic dissemination of cancers), sekundaarinen syöpä (metastatic cancer, secondary cancer), HIV-tartuntaa seuraava syöpä (metastatic cancer, secondary cancer), akuutti metastaasioireyhtymä (acute metastatic progression). (various references) | ||||||||||||||||
French | syndrome métastatique aigu (acute metastatic progression), infarctus par métastase (metastatic infarct), goutte métastatique (metastatic gout), encéphalite par embolie cérébrale (embolic metastatic encephalitis), encéphalite métastatique (metastatic encephalitis), dissémination métastatique des cancers (metastatic dissemination of cancers), cellule métastatique tueuse (metastatic killer cell), cellule métastatique circulante (metastatic cell in circulation), cancer secondaire (metastatic cancer), calcinose métastatique (metastatic calcinosis), arthrite métastatique (metastatic arthritis), abcès métastatique (metastatic abscess), épisclérite métastatique furonculiforme de Kramer (furunculoid metastatic episcleritis), épisclérite furonculiforme de Kramer (furunculoid metastatic episcleritis). (various references) | ||||||||||||||||
German | metastatischer Infarkt (metastatic infarct), metastatischer Abszess (metastatic abscess), metastatische Gicht (metastatic gout), metastatische Arthritis (metastatic arthritis), Kramer Krankheit (furunculoid episcleritis, furunculoid metastatic episcleritis), Episcleritis metastatica furunculiformis (furunculoid episcleritis, furunculoid metastatic episcleritis), Episcleritis furunculiformis (furunculoid episcleritis, furunculoid metastatic episcleritis), Encephalitis metastatica (metastatic encephalitis), embolische Herdenzephalitis (embolic metastatic encephalitis), Calcinosis metastatica (metastatic calcinosis), Arthritis infectiosa specifica (metastatic arthritis). (various references) | ||||||||||||||||
Greek | μεταστατικό έμφρακτο (metastatic infarct), μεταστατικό απόστημα (metastatic abscess), μεταστατική αρθρίτις (metastatic arthritis), μεταστατική ασβέστωσις (metastatic calcinosis), μεταστατική ουρική αρθρίτις (metastatic gout), μεταστατική διασπορά του καρκίνου (metastatic dissemination of cancers), οξύ μεταστατικό σύνδρομο (acute metastatic progression), δευτεροπαθής καρκίνος (metastatic cancer, secondary cancer). (various references) | ||||||||||||||||
Italian | tumore secondario (metastatic cancer, secondary cancer), sindrome metastatica acuta (acute metastatic progression), encefalite metastatica embolica (embolic metastatic encephalitis), disseminazione metastatica dei tumori (metastatic dissemination of cancers), cellula metastatica killer (metastatic killer cell), cellula metastatica in circolo (metastatic cell in circulation), ascesso emostatico (metastatic abscess), artrite metastatica (metastatic arthritis). (various references) | ||||||||||||||||
Pig Latin | etastaticmay gota metastática (metastatic gout), enfarte metastático (metastatic infarct), encefalite metastática embólica (embolic metastatic encephalitis), artrite metastática (metastatic arthritis), abcesso metastático (metastatic abscess). (various references) metátasis de evolución aguda (acute metastatic progression), metástasis asesina (metastatic killer cell), tumor secundario (metastatic cancer, secondary cancer), infarto metastásico (metastatic infarct), gota metastásica (metastatic gout), encefalitis por embolia metastásica (embolic metastatic encephalitis), diseminación metastásica (metastatic dissemination of cancers), calcinosis metastásica (metastatic calcinosis), célula metastásica en circulación (metastatic cell in circulation), artritis metastásica (metastatic arthritis), absceso metastásico (metastatic abscess). (various references) | ||||||||||||||||
Derivations | |
Words beginning with "metastatic": metastatically. (additional references) | |
| Source: compiled by the editor, based on several corpora (additional references). | |
| Words rhyming with "metastatic" (pronounced 'Met`a*stat"ic'): Abdominothoracic, Abietic, Abietinic, Abiogenetic, Ablastemic, Abrahamic, Acerbic, Aceric, Acetonic, Achromatic, Achronic, Acidic, Acidific, Aclinic, Acologic, Acopic, Acroatic, Acrobatic, Acrocephalic, Acromonogrammatic, Acrotic, Acrylic, Actinic, Actinolitic, Actinophonic, Adelocodonic, Adenographic, Adenotomic, Adiabatic, Adiactinic, Adipic, Adipolytic, Adonic, Adriatic, Adynamic, AEolotropic, Aerobiotic, Aerodynamic, Aerolitic, AEsthesodic, Agamic, Agamogenetic, Agenesic, Agnatic, Agonic, Agonothetic, Agraphic, Agrypnotic, Albinotic, Alcaic. (additional references) |
Scrabble® Enable2K-Verified Anagrams | |
| Words within the letters "a-a-c-e-i-m-s-t-t-t" | |
-1 letter: catamites, masticate. | |
-2 letters: catamite, cattiest. | |
-3 letters: astatic, catties, etatism, etatist, satiate, sematic, statice, tatamis, tatties. | |
-4 letters: amices, attest, attics, camisa, camise, casita, cattie, mastic, mattes, misact, misate, miseat, samite, stacte, static, tamest, tatami, tattie. | |
-5 letters: aceta, acmes, aecia, amias, amice, amies, atmas, attic, camas, cames, caste, cates, cesta, cesti, cites, emits, items, maces, maist, mates. | |
| Words containing the letters "a-a-c-e-i-m-s-t-t-t" | |
+3 letters: magnetostatic, transmittance. | |
+4 letters: automaticities, metastatically, transmittances. | |
+5 letters: circumstantiate, metamathematics. | |
| Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro. | |
Hexadecimal (or equivalents, 770AD-1900s) (references)4D 65 74 61 73 74 61 74 69 63 |
| Leonardo da Vinci (1452-1519; backwards) (references)
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| American Sign Language (origins from 1620-1817 in Italy and, especially, France) (references)
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| Semaphore (1791, in France) (references)
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| Braille (1829, in France) (references)
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Morse Code (1836) (references)-- . - .- ... - .- - .. -.-. |
| Dancing Men (Sir Arthur Conan Doyle, 1903) (references)
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Binary Code (1918-1938, probably earlier) (references)01001101 01100101 01110100 01100001 01110011 01110100 01100001 01110100 01101001 01100011 |
HTML Code (1990) (references)M e t a s t a t i c |
ISO 10646 (1991-1993) (references)004D 0065 0074 0061 0073 0074 0061 0074 0069 0063 |
| British Sign Language (Fingerspelling, BSL; 1992, British Deaf Association Dictionary of British Sign Language) (references)
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Encryption (beginner's substitution cypher): (references)47718667858667867569 |
| 1. Definition 2. Crosswords 3. Usage: Commercial 4. Images: Photo Album | 5. Quotations: Non-fiction 6. Usage Frequency 7. Expressions 8. Expressions: Internet | 9. Translations: Modern 10. Derivations 11. Rhymes 12. Anagrams | 13. Orthography 14. Bibliography |
Copyright © Philip M. Parker, INSEAD. Terms of Use.
| Note to the press & webmasters - this dictionary can be linked, indexed, or referred to using the following non-English expressions: woordeboek, fjalor, معجم, قاموس, diccionariu, речник, diccionari, diksyonario, diksinario, 字典, gérlyver, slovník, ordbog, woordenboek, shimiyuc p'anca, orðabók, orðbók, dictionnaire, wurdboek, wörterbuch, λεξικό, אוצר מילים, szótár, uqausiit tukingit, dizionario, 字引 , じい, じびき, じて", ディクショナリー , じり", じしょ, '"かい, ディクショナリ , 사 , dizionari, recnik, fockleyr, dikshonario, słownik, dicionário, dicţionar, dicziunari, словарь, lolomi fefiloi, foclair, abardair, faclair, briathrachan, pukuntau, leksikon, rečnik, vocabbulariu, diccionario, sí-chazamagâma, ordbok, lexikon, พจนานุกรม, sözlük, ansiklopedik sözlük, словник, довідник, có tính chất sách vở, geirlyfr, geiriadur, for dictionary; definisie, qartësi, përcaktim, saktësi, الوضوحية في الشيء, حد, تحديد, تعريف, التحديد, الإيضاحية, яснота, сила, очертания, дефиниция, 定義 , 定义, definice, deskriptordefinition, definitie, määritelmä, définition, ορισμός, "'"ר", "'בל", meghatározás, definíció, definizione, 確定 , ディーゼル電気車 , デ'ドロ酢酸 , デフィニション , ディフィニション , ていぎ, かくてい, 의, geyrid, meenaghey, keeayllaght, baght, definishon, definição, definiţie, determinare, definire, определение, definicija, definición, definition, açıklama, belirleme, belirtme, kesinleştirme, tanım, tarif, seçiklik, tanımlama, чіткість, тлумачення, виразність, визначення, дефініція, ясність, чітка чутність, sự định rõ, sự định nghĩa, lời định nghĩa sự định, diffiniad, darnodiad, for definition; vertaling, transferim, transmetim, ترجمة من لغة أجنبية للغة الأم, ترجمة, إفتتان, транслация, огъване, превод, предаване, поддаване, тълкуване, превеждане, 翻译, překlad, oversættelse, translatie, taajuusmuutos, translaatio, traduction, oersetting, Übersetzung, μετάφραση, תור'מ ות, תר'ום, "עתק", "עתק, fordítás, traduzione, 翻訳 , へい"ういどう, やくしょ, やくしゅつ, "うどく, ほ"やく, トランスレーション , やくじゅつ, ほ"やくしょ, 번역, tradukshon, tradução, translaţie, tãlmãcire, traducere, сдвиг, трансляция, перемещение, перевод, tumačenje, traducción, översättning, tercüme, процес перекладу, переклад, пояснення, переміщення, sự dịch, sự biến th nh sự giải thích, trosiad, for translation; Deens, danisht, danishte, لغة الدانمركية, نوع كعك, دانماركي, датски език, датски, Daniko, 丹麦语, dánský, dánština, danskur, danskt, tanskalainen, danois, Deensk, dänisch, δανικόσ, δανόσ, עו'ת שמרים, " י, dán, danska, Danmhairgis, danese, 덴마크, Danvargish, Danvargagh, danes, dinamarquês, danez, датский, danski, danski jezik, danés, dansk, danimarkalı, danimarka dili, датський, датська мова, tiếng Đan-mạch, for Danish; Nederlands, Hollands, holandez, هولندي, اللغة الهولندية, холандски, немски език, холандски език, холандците, немски, Olandes, 菏蘭語 , 荷兰语, holandský, nizozemský, hollandsk, hollendskt, hollantilainen, néerlandais, Nederlânsk, holländisch, ολλανδικόσ, ολλανδόσ, holandisht, "ול "י, holland, hollenskur, Ollainnis, olandese, 네덜란", Belanda, Ollanish, Germaanish, Tatimana, nederlandsk, ulandes, hulandes, holandês, neerlandés, olandez, nemţesc, limba olandezã, german, голландский, holanđanin, u škripcu, holandski, holandés, bakratongo, holländsk, ชาวเนเธอร์แลน"์, เกี่ยวกับเนเธอร์แลน"์, รรยา, alman, eş, flemenkçe, holandaca, hollanda, karı, hollandalı, hollandalılara özgü olan, Hollandali, hollanda'ya ait, голландська мова, голландський, ngôn ngữ khó hiểu, "b xã", for Dutch; Fins, finlandez, finlandishte, finlandisht, اللغة الفنلندية, فنلندية, فنلندي, фински език, фински, Pinlandino, 芬蘭語 , 芬兰语, finský, finskt, suomi, suomalainen, finnois, Finlandaise, finlandais, finnisch, φινλανδικόσ, פי י, finn, finnskur, finnska, finlandese, 핀란", Fynlannish, Fynlannagh, finlandês, finês, finlandezã, финский, Finisi, finski jezik, finski, finlandés, finés, finsk, fince, finlandiya'ya özgü, фінська мова, фінський, tiếng Phần-lan, for Finnish; Franse taal, Frans, franceze, francez, frëngjisht, frëng, frëngjishte, فرنسي, اللغة الفرنسية, الشعب الفرنسي, gall, френски език, френски, Pranses, 法國 , 法文 , 法語 , 法语, francouzština, francouzský, franskur, franskt, ranskalainen, français, Frânsk, französisch, γάλλοσ, γαλλικόσ, γαλλική γλώσσα, γαλλίδα, צרפתי, צרפתית, francia, Fraincis, francese, フレコン化 , フランス" , 仏文 , 仏 , ふつぶ", フレンチ , フランセ , ふつ, "랑스, Perancis, Ny Frangee, Mooinjey ny Frank, frances, franses, francês, francezii, francezã, franţuzesc, franţuzeşte, французский, Falani, francuski jezik, francuski, francuzi, francés, sí-Fulentji, fransk, franska, fransızca, Fransiz, fransızca ile ilgili, fransız, fransa ile ilgili, французька мова, французький, Ffrengig, isiFulentshi, for French; Duits, Duitser, Duitse taal, Germaan, gjerman, ضرب من الرقص, جرماني, المانية, الماني, اللغة الألمانية, роден, германски, немски език, немски, немец, готически, германец, 德語 , 德语, 德文 , 德國 , nìmecký, nìmec, tysker, Duitse, týskur, týskt, týskari, saksalainen, Allemand, Dútsk, Deutsche, Deutsch, "ερμανός, gjermanisht, 'רמ י, 'רמ ית, német, þjóðverji, þýskur, GearmÚnach, GearmÚinis, tedesco, ジプシー音楽 , ジャーマン , 독일, todesch, Germaanagh, Garmane, Germaanish, Carmane, aleman, Niemiec, niemiecki, alemão, alemand, neamţ, немецкий, Siamani, germanski, alemán, Tudesku, Doysri, mjeremani, mdachi, sí-Jalimáne, tysk, เยอรมัน, าษาเยอรมัน, Alman, німкеня, німецький, німець, $sisters german$ chị em ruột, $cousin german$ anh chị em con chú bác ruột, sister, Almaenwr, isiJalimane, iliJalimane, iJalimane, for German; Grieks, Griek, الإغريقي, يوناني, اللغة اليونانية, Griegu, гръцки език, гръцки, грък, Griyego, 希臘語 , 希腊语, řecký, řeètina, řek, græker, grikst, kreikkalainen, grec, Gryk, Gryksk, Gryks, grieche, ελληνικόσ, 'Ελληνας, יו ית, יו י, görög, Grikki, greco, ギリシア語 , ギリシア", 그리스, Greagish, Greagagh, grego, grèc, greacã, греческий, Eleni, grk, grčki jezik, grčki, griego, grek, Yunanli, yunanlı, yunanca, yunan, Rumca, yunanistan'a ait, rum, грек, гречанка, грецька мова, грецький, kẻ cắp b gi gặp nhau, quân bạc bịp tôi không thể hiểu được điều đó thật l kỳ phùng địch thủ, người Hy-lạp tiếng Hy-lạp kẻ bịp bợm, kẻ lừa đảo, Groegwr, for Greek; Italianer, Italiaans, Italiaan, شخص إيطالي, اللغة الإيطالية, الإيطالي, إيطالي, Italianu, италиански език, италиански, италианец, Italyano, 意大利 , 意大利語 , 意大利语, italština, italský, ital, italiener, italienskt, italialainen, Italien, Italjaansk, italienisch, Ιταλός, italisht, איטלקי, איטלקית, olasz, Ítali, IodÚilis, italiano, 이탈리아, Iddaalish, Włoch, italianã, italienesc, italieneşte, italian, итальянский язык, итальянский, итальянец, Italia, italijanski, italijanski jezik, italijan, sí-Taliyáne, italienare, italiensk, italienska, เกี่ยวกับอิตาลี, ชาวอิตาลี, าษาอิตาลี, italyanca, italyan, італі"ць, італійська мова, італійський, італійка, for Italian; Portugees, portugez, portugalisht, اللغة البرتغالية, البرتغالية, البرتغالي, португалски език, португалски, португалец, Potuges, 葡萄牙语, 葡萄牙人 , 葡萄牙語 , portugalský, portugiser, portugisiskt, portugalilainen, portugais, Portugeesk, portugiesisch, πορτογάλοσ, ορτογάλος, portugál, Portaingéilis, portoghese, ポルトガル語 , ポルトガル", 포르투갈, Portiugish, Portiugagh, portugues, Portugalczyk, português, portughez, португальский, portugalski jezik, portugalski, portugalac, portugués, Mreno, si-Putúkezi, portugis, portekiz, Portekízlí, portekizli, portekizce, португальська мова, португальський, португалець, người B"-đ o-nha tiếng B"-đ o-nha, for Portuguese; Spaans, Spaanse taal, spanjoll, اللغة الأسبانية, الأسبانية, أسباني, испански език, испански, espanyoles, Espanyol, 西班牙语, 西班牙文 , 西班牙語 , španìlský, španìlština, spanskt, espanjalainen, espagnol, Spaansk, spanisch, ισπανικά, ισπανικόσ, ισπανοί, karaiñe'êmegua, ספר"ית, ספר"י, spanyol, SpÚinnis, spagnolo, スペイン語 , スパイ罪 , スペイン", スパニッシュ , 스페인, Spaainagh, Spaainish, spañó, espanhol, espanhòl, spaniolesc, spanioleşte, spaniol, испанский, Sipaniolo, španski jezik, španski, español, spanska språk, spansk, ispanyollar, ispanyolca, ispanyol, іспанська мова, іспанський, for Spanish; 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