Copyright © Philip M. Parker, INSEAD. Terms of Use.

INTERLEUKIN-2

Specialty Definition: INTERLEUKIN-2

DomainDefinition

Health

Chemical mediator produced by activated T lymphocytes and which regulates the proliferation of T cells, as well as playing a role in the regulation of NK cell activity. (references)
 Soluble substances elaborated by antigen- or mitogen-stimulated T-lymphocytes which induce DNA synthesis in naive lymphocytes. (references)

Medicine

Interleukin-2:chemical mediator produced by activated T lymphocytes and which regulates the proliferation of T cells, as well as playing a role in the regulation of NK cell activity. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Crosswords: INTERLEUKIN-2

Specialty definitions using "INTERLEUKIN-2": aldesleukinBiomed 101hu14.18-interleukin-2 fusion proteinInterleukin-1, Interleukin-7leuvectin, Lymphocytes, Tumor-InfiltratingNG-monomethyl-L-arginineTh1 Cells. (references)

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Commercial Usage: INTERLEUKIN-2

DomainTitle

Books

  • Interleukin-2 and Killer Cells in Cancer (reference)

    (more book examples)

Source: compiled by the editor from various references; see credits.

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Photo Album: INTERLEUKIN-2

ThumbnailDescription & CreditThumbnailDescription & Credit

The patient is a 53 year old woman with metastatic melanoma to multiple subcutaneous sites and retroperitoneum. She was treated with tumor infiltrating lymphocytes (TILs) transduced with the gene for tumor necrosis factor (TNF). Pretreatment biopsy shows multiple live melanoma cells with little lymphoid infiltrate. Following treatment with TNF gene modified TILs plus interleukin-2, a biopsy of another lesion showed massive coagulative necrosis of the tumor with no viable tumor seen. This is a typical picture seen in experimental animals treated with tumor necrosis factor. This patient has had a substantial objective response that is currently ongoing at nine months following initiation of treatment. Credit: Unknown photographer/artist.

Mice were injected with mouse sarcoma cells amd treated 3 days later when many micro-metastatic tumor foci were evident in the lungs. Lungs on the left were treated with saline. The lungs on the right were treated with lymphokine activated killer (LAK) cells plus recombinant interleukin-2. Greater than 250 sarcoma metastases are seen in the lungs of saline treated mice. This number is significantly reduced to less than 12 in mice receiving LAK cells plus recombinant interleukin-2. Normal mouse lung is 1 inch long. Credit: Unknown photographer/artist.

Source: pictures compiled by the editor from various references; see picture credits.

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Non-Fiction Usage: INTERLEUKIN-2

SubjectTopicQuote

Health

In numerous studies, researchers have supplied patients with extra amounts of immune stimulants, such as interleukin-2, in the hope that they will improve the body's ability to fight CNS cancer. (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Usage Frequency: INTERLEUKIN-2

"INTERLEUKIN-2" is generally used as a noun (singular) -- approximately 92.31% of the time. "INTERLEUKIN-2" is used about 26 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted)
Parts of SpeechPercentUsage per
100 Million Words
Rank in English
Noun (singular)92.31%2471,196
Adjective (general or positive)7.69%2245,945
                    Total100.00%26N/A

Source: compiled by the editor from several corpora; see credits.

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Expression: INTERLEUKIN-2

Hyphenated Usage

Containing "INTERLEUKIN-2": hu14.18-interleukin-2 fusion protein.

Source: compiled by the editor from various references; see credits.

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Modern Translation: INTERLEUKIN-2

Language Translations for "INTERLEUKIN-2"; alternative meanings/domain in parentheses.

French

  

interleukine-2, IL-2, facteur de croissance des lymphocytes T. (various references)

   

Pig Latin

  

interleukin-2ay

   

Spanish

  

interleuquina-2 (IL-2, T-cell growth factor, TCGF, thymocyte stimulating factor). (various references)

Source: compiled by the editor from various translation references.

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Anagrams: INTERLEUKIN-2

Scrabble® Enable2K-Verified Anagrams

Words within the letters "2-e-e-i-i-k-l-n-n-r-t-u"

-1 letter: interleukin.

-3 letters: interline, interlink.

-4 letters: runelike, tinklier, tunneler.

-5 letters: interne, inutile, kernite, kinetin, lenient, lintier, netlike, neurine, niterie, nitrile, nunlike, nutlike, retinue, reunite, tinkler, tinlike, tinnier, trunnel, urnlike, uterine.

Source: compiled by the editor from various references; see credits.

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INDEX

1. Crosswords
2. Usage: Commercial
3. Images: Photo Album
4. Quotations: Non-fiction
5. Usage Frequency
6. Expressions
7. Translations: Modern
8. Anagrams
9. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.