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INTEGRASE

Specialty Definition: INTEGRASE

DomainDefinition

Health

An enzyme that inserts DNA into the host genome. It is encoded by the pol gene of retroviruses and also by temperate bacteriophages, the best known being bacteriophage lambda. EC 2.7.7.-. (references)

Medicine

Enzyme which is used to integrate the DNA into the cell's nucleus. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Specialty Definition: Integrase

(From Wikipedia, the free Encyclopedia)

HIV integrase is an 32 kDa protein produced from the C-terminal portion of the Pol gene product. The integrase protein contains three domains: an N-terminal HH-CC zinc finger domain believed to be partially responsible for multimerization, a central catalytic domain and an C-terminal DNA binding domain. Integrase is responsible for the integration of proviral DNA into the host genome, which is essential for HIV replication. Integrase, therefore, remains a promising potential target for new anti-HIV therapeutics.

See also: retrovirus

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Integrase."

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Crosswords: INTEGRASE

Specialty definitions using "INTEGRASE": HIV Integrase, HIV Integrase Inhibitorsintegrase inhibitor, Integrase Inhibitors. (references)

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Usage Frequency: INTEGRASE

"INTEGRASE" is generally used as a noun (singular) -- approximately 100.00% of the time. "INTEGRASE" is used about 4 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted)
Parts of SpeechPercentUsage per
100 Million Words
Rank in English
Noun (singular)100%4175,879

Source: compiled by the editor from several corpora; see credits.

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Expressions: INTEGRASE

Expressions using "INTEGRASE": HIV Integrase HIV Integrase Inhibitors integrase inhibitor Integrase Inhibitors. Additional references.

Source: compiled by the editor from various references; see credits.

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Frequency of Internet Keywords: INTEGRASE

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

integrase inhibitor

2
Source: compiled by the editor from various references; see credits.

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Modern Translation: INTEGRASE

Language Translations for "INTEGRASE"; alternative meanings/domain in parentheses.

Danish

  

anti-integrase (integrase inhibitor). (various references)

   

Dutch

  

integrase. (various references)

   

Finnish

  

anti-integraasi (integrase inhibitor). (various references)

   

French

  

intégrase. (various references)

   

German

  

Integrase. (various references)

   

Greek 

  

αντι-ενσωματάση (integrase inhibitor). (various references)

   

Italian

  

integrasi. (various references)

   

Pig Latin

  

integraseay

   

Spanish

  

integrasa. (various references)

Source: compiled by the editor from various translation references.

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Anagrams: INTEGRASE

Scrabble® Enable2K-Verified Anagrams

Direct Anagrams: agentries, gratinees, reseating, stingaree.

Words within the letters "a-e-e-g-i-n-r-s-t"

-1 letter: anergies, angriest, arenites, arsenite, astringe, estrange, ganister, gantries, gentries, gesneria, granites, grantees, gratinee, greatens, ingrates, integers, interage, negaters, rangiest, reagents, reesting, resinate, sergeant, stearine, steering, trainees.

-2 letters: aeriest, aigrets, anestri, antsier, arenite, argents, earings, earnest, eastern, easting, eatings, enrages, entires, entries, erasing, ergates, etesian, gainers, gaiters, garnets, gastrin, gerents, granite, grantee, gratine.

 Words containing the letters "a-e-e-g-i-n-r-s-t"
 

+1 letter: argentines, argentites, denigrates, estreating, generalist, germinates, integrates, interstage, steamering, stingarees, tangerines.

 

+2 letters: desecrating, ergotamines, everlasting, featherings, garnierites, generalists, generations, greasepaint, impregnates, intergrades, magnetizers, nearsighted, nitrogenase, pageantries, rearresting, reasserting, refastening, regimentals, relegations, remastering, segregating, segregation, sergeanties, vegetarians, weatherings.

 

+3 letters: abridgements, antiestrogen, asseverating, bespattering, desiderating, disagreement, disintegrate, everlastings, eviscerating, exasperating, ferrimagnets, fragmentizes, freestanding, generalities, generatrices, glycerinates, granitewares, greasepaints, interchanges, interrogates, libertinages, mastersinger, nitrogenases, peregrinates, predesignate, realignments, reassignment, reescalating, reestimating, refrigerants, reintegrates, renegotiates, replastering, segregations, seronegative, straightened, straightener, superheating, talebearings, tragediennes, vinaigrettes.

Source: compiled by the editor from various references; see credits.

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INDEX

1. Crosswords
2. Usage Frequency
3. Expressions
4. Expressions: Internet
5. Translations: Modern
6. Anagrams
7. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.