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Definition: Hodgkin's Disease |
Hodgkin's DiseaseNoun1. A malignant disorder in which there is progressive (but painless) enlargement of lymph tissue followed by enlargement of the spleen and liver. Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved. |
| Domain | Definitions |
Health | A malignant disease of the lymphatic system that is characterized by painless enlargement of lymph nodes, the spleen, or other lymphatic tissue. It is sometimes accompanied by symptoms such as fever, weight loss, fatigue, and night sweats. (references) |
Source: compiled by the editor from various references; see credits. | |
(From Wikipedia, the free Encyclopedia)
Unlike other lymphomas, whose incidence increases with age, Hodgkin's lymphoma has a bimodal incidence curve: that is, it occurs more frequently in two separate age groups, the first being young adulthood (age 15-35), the second being in those over 50 years old. It is more common in males.
Swollen, but non-painful, lymph nodes are the most common sign of Hodgkin's disease, often occurring in the neck. The lymph nodes of the chest are often affected and these may be noticed on chest X-ray.
About one-third of people with Hodgkin's disease may also notice some systemic symptoms, such as low-grade fever, night sweats, weight loss, or fatigue.
Hodgkin's disease must be distinguished from non-cancerous causes of lymph node swelling (such as various infections) and from other types of cancer. Definitive diagnosis is by lymph node biopsy (removal of a lymph node for pathological examination).
Hodgkin's disease can be sub-classified by histological type. The cell histology in Hodgkin's lymphoma is not as important as it is in non-Hodgkin's lymphoma: the treatment and prognosis in Hodgkin's lymphoma depend on the stage of disease rather than the cell type.
After Hodgkin's disease is diagnosed, a patient will be staged: that is, they will undergo a series of tests and procedures which will determine what areas of the body are affected. These procedures will alway include documentation of their histology, a physical examination, blood tests, chest X-Ray, CT scans or MRI (magnetic resonance imaging) scans of the chest, abdomen and pelvis, and a bone marrow biopsy. Some patients will also require liver biopsy, lymphangiograms, gallium scans, bone scans, and surgical laparotomy, which involves opening the abdominal cavity and visually inspecting for tumors.
On the basis of this staging, the patient will be classified according to a staging classification (the Ann Arbor staging classification scheme is a common one):
Patients with early stage disease (IA or IIA) are effectively treated with radiation therapy. Patients with later disease (III, IVA, or IVB) are treated with combination chemotherapy alone. Patients of any stage with a large mass in the chest are usually treated with combined chemotherapy and radiation therapy.
Those undergoing chemotherapy require a minimum of six cycles and may require longer treatment.
With appropriate treatment, over 85% of Hodgkin's disease cases are curable.
The American National Cancer Institute's "Hodgkin's Lymphoma Home Page" is http://www.cancer.gov/cancer_information/cancer_type/hodgkins_disease/Epidemiology
Symptoms
Diagnosis
Staging
The absence of systemic symptoms is signified by adding 'A' to the stage; the presence of systemic symptoms is signified by adding 'B' to the stage.Treatment
Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Hodgkin's disease."
Crosswords: Hodgkin's Disease |
| English words defined with "Hodgkin's disease": Hodgkin ♦ lomustine ♦ procarbazine ♦ Thomas Hodgkin. (references) |
| Specialty definitions using "Hodgkin's disease": Antigens, CD30 ♦ HLA-A1 Antigen ♦ Lymphoma, Non-Hodgkin, Lymphomatoid Papulosis ♦ Mechlorethamine ♦ Reed-Sternberg cell ♦ stage I Hodgkin's disease, stage II Hodgkin's disease, stage III Hodgkin's disease, stage IV Hodgkin's disease. (references) |
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Source: compiled by the editor from various references; see credits. | |
| Subject | Topic | Quote |
Health | Except in Hodgkin's disease, treatment is usually given to prevent the spread of disease to the brain and spinal column. (references) | |
Lymphomas have been broadly divided into Hodgkin's disease and non-Hodgkin's lymphomas, which include a number of diseases. (references) | ||
In the case of Hodgkin's disease, radiation therapy is highly effective for localized disease and has been the main form of treatment. (references) | ||
Source: compiled by the editor from ICON Group International, Inc.; see credits. | ||
Expressions using "Hodgkin's disease": stage I Hodgkin's disease ♦ stage II Hodgkin's disease ♦ stage III Hodgkin's disease ♦ stage IV Hodgkin's disease. Additional references. | |
| Source: compiled by the editor from various references; see credits. |
| Language | Translations for "Hodgkin's disease"; alternative meanings/domain in parentheses. | ||||||||||
Danish | Hodgkins sygdom stadium IV (stage IV Hodgkin's disease), Hodgkins sygdom stadium III (stage III Hodgkin's disease), Hodgkins sygdom stadium II (stage II Hodgkin's disease), Hodgkins sygdom stadium I (stage I Hodgkin's disease). (various references) | ||||||||||
Dutch | stadium IV van de ziekte van Hodgkin (stage IV Hodgkin's disease), stadium III van de ziekte van Hodgkin (stage III Hodgkin's disease), stadium II van de ziekte van Hodgkin (stage II Hodgkin's disease), stadium I van de ziekte van Hodgkin (stage I Hodgkin's disease). (various references) | ||||||||||
Finnish | Hodgkinin taudin IV vaihe (stage IV Hodgkin's disease), Hodgkinin taudin III vaihe (stage III Hodgkin's disease), Hodgkinin taudin II vaihe (stage II Hodgkin's disease), Hodgkinin taudin I vaihe (stage I Hodgkin's disease). (various references) | ||||||||||
French | stade IV de la maladie de Hodgkin (stage IV Hodgkin's disease), stade III de la maladie de Hodgkin (stage III Hodgkin's disease), stade II de la maladie de Hodgkin (stage II Hodgkin's disease), stade I de la maladie de Hodgkin (stage I Hodgkin's disease). (various references) | ||||||||||
Greek | στάδιο ΙV νόσου Hodgkin (stage IV Hodgkin's disease), στάδιο ΙΙΙ νόσου Hodgkin (stage III Hodgkin's disease), στάδιο ΙΙ νόσου Hodgkin (stage II Hodgkin's disease), στάδιο Ι νόσου Hodgkin (stage I Hodgkin's disease). (various references) | ||||||||||
Italian | stadio terzo del morbo di Hodgkin (stage III Hodgkin's disease), stadio IV della malattia di Hodgkin (stage IV Hodgkin's disease), stadio IV del morbo di Hodgkin (stage IV Hodgkin's disease), stadio III della malattia di Hodgkin (stage III Hodgkin's disease), stadio II della malattia di Hodgkin (stage II Hodgkin's disease), stadio II del morbo di Hodgkin (stage II Hodgkin's disease), stadio I della malattia di Hodgkin (stage I Hodgkin's disease), stadio I del morbo di Hodgkin (stage I Hodgkin's disease). (various references) | ||||||||||
Japanese Kanji | ホジキン病 (hop step and jump, hospice, hospital, hospitalism, hospitality, host, host club, host computer, host country, host family, hostel, hostess, host-name, phosgene, triple jump). (various references) | ||||||||||
Japanese Katakana | ホジキンびょう. (various references) | ||||||||||
Pig Latin | odgkin'shay iseaseday estadio IV de la enfermedad de Hodgkin (stage IV Hodgkin's disease), estadio III de la enfermedad de Hodgkin (stage III Hodgkin's disease), estadio II de la enfermedad de Hodgkin (stage II Hodgkin's disease), estadio I de la enfermedad de Hodgkin (stage I Hodgkin's disease). (various references) | ||||||||||
Scrabble® Enable2K-Verified Anagrams | |
| Words within the letters "'-a-d-d-e-e-g-h-i-i-k-n-o-s-s-s" | |
-5 letters: dodginesses, giddinesses. | |
| Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro. | |
Hexadecimal (or equivalents, 770AD-1900s) (references)48 6F 64 67 6B 69 6E 27 73 44 69 73 65 61 73 65 |
| Leonardo da Vinci (1452-1519; backwards) (references)
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Binary Code (1918-1938, probably earlier) (references)01001000 01101111 01100100 01100111 01101011 01101001 01101110 00100111 01110011 00100000 01000100 01101001 01110011 01100101 01100001 01110011 01100101 |
HTML Code (1990) (references)H o d g k i n ' s   D i s e a s e |
ISO 10646 (1991-1993) (references)0048 006F 0064 0067 006B 0069 006E 0027 0073 0044 0069 0073 0065 0061 0073 0065 |
Encryption (beginner's substitution cypher): (references)42817073777580985238758571678571 |
| 1. Definition 2. Crosswords 3. Usage: Commercial 4. Quotations: Non-fiction | 5. Expressions 6. Translations: Modern 7. Anagrams 8. Orthography | 9. Bibliography |
Copyright © Philip M. Parker, INSEAD. Terms of Use.
