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Haloperidol

Definition: Haloperidol

Haloperidol

Noun

1. Tranquilizer (trade name Haldol) used to treat some psychotic disorders and Tourette's syndrome.

Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved.
 



Specialty Definitions: Haloperidol

DomainDefinitions

Medicine

Butyrophenone derivative. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Specialty Definition: Haloperidol

(From Wikipedia, the free Encyclopedia)

Haloperidol (Haldol) is a conventional antipsychotic butyrophenone drug. It was developed in 1957 by Belgian company Janssen and submitted to first clinical trials in Belgium in the same year. After being rejected by US company Searle due to side effects it was later marketed in the US by McNeil Laboratories.

The drug is used in the control of the symptoms of acute psychosis, acute schizophrenia or manic phases, hyperactivity, and also to control aggression, agitation, and psychotic thinking. It has also been used in delusional individuals and to treat Tourette's syndrome. It has been used in the treatment of a number of other conditions but without widespread approval. It has strong tranquiliser effects and works by acting on the dopamine receptors in the brain.

Haloperidol is an odourless white to yellow crystalline powder. Its chemical name is 4-[4-(p-chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone and its empirical formula is C21H23ClFNO2

The drug is noted for its strong extrapyramidal side-effects. Common side effects include dry-mouth, lethargy, muscle-stiffness, muscle-cramping, tardive dyskinesia, tremors, and weight-gain. The risk of tardive dyskinesia is around 4% in younger patients, higher than in most other antipsychotic drugs, in patients over the age of 45 the percentage afflicted can be much higher. These symptoms can be permanent, despite discontinuation of the medication. Neuroleptic malignant syndrome (NMA) is a possible side effect of long-term use.

As well as Haloperidol the decanoate ester Haloperidol decanoate can be used or Haloperidol Lactate. The decanoate has a greatly extended duration of effect and its structural formula is 4-(4-chlorophenyl)-1-1[4-(4-fluorophenyl)-4-oxobutyl]-4 piperidinyl decanoate, which looks like:

and is generally administered via an intramuscular injection usually in the buttocks.

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Haloperidol."

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Synonym: Haloperidol

Synonym: Haldol (n). (additional references)

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Crosswords: Haloperidol

Specialty definitions using "haloperidol": Spiperone. (references)

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Non-Fiction Usage: Haloperidol

SubjectTopicQuote

Health

In general atypical antipsychotic medications are more successful than older drugs such as haloperidol. (references)

Short-term side effects of haloperidol and pimozide include muscular rigidity, drooling, tremor, lack of facial expression, slow movement, and restlessness. (references)

Some patients who require medication to reduce the frequency and intensity of the tic symptoms may be treated with neuroleptic drugs such as haloperidol and pimozide. (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Usage Frequency: Haloperidol

"Haloperidol" is generally used as a noun (singular) -- approximately 100.00% of the time. "Haloperidol" is used about 6 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted)
Parts of SpeechPercentUsage per
100 Million Words
Rank in English
Noun (singular)100%6143,867

Source: compiled by the editor from several corpora; see credits.

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Frequency of Internet Keywords: Haloperidol

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

haloperidol

81

haloperidol side effects

3

haloperidol decanoate novaplus

2

haldol haloperidol

2
Source: compiled by the editor from various references; see credits.

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Modern Translations: Haloperidol

Language Translations for "haloperidol"; alternative meanings/domain in parentheses.

Danish

  

haloperidol. (various references)

   

Dutch

  

haloperidol. (various references)

   

Finnish

  

haloperidoli. (various references)

   

French

  

halopéridol. (various references)

   

German

  

Haloperidol. (various references)

   

Greek 

  

αλοπεριδόλη. (various references)

   

Italian

  

aloperidolo, aloperidol. (various references)

   

Korean 

  

로페리돌. (various references)

   

Pig Latin

  

aloperidolhay.(various references)

   

Portuguese

  

haloperidol. (various references)

   

Spanish

  

haloperidol. (various references)

   

Swedish

  

haloperidol. (various references)

Source: compiled by the editor from various translation references.

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Derivations: Haloperidol

Derivations

Words beginning with "haloperidol": haloperidols. (additional references)

Source: compiled by the editor, based on several corpora (additional references).

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Anagrams: Haloperidol

Scrabble® Enable2K-Verified Anagrams

Words within the letters "a-d-e-h-i-l-l-o-o-p-r"

-3 letters: arillode, hallooed, hilloaed, holloaed, pillared.

-4 letters: airhole, dallier, dariole, dialler, dipolar, ephoral, halloed, haploid, harelip, helipad, hilloed, hirpled, hollaed, holloed, hoodier, leopard, leporid, loopier, oedipal, oilhole, pallier, parodoi, paroled, peloria, perilla, pollard, predial, prilled, rallied, ralphed, raphide, redpoll.

-5 letters: aliped, allied, apollo, ariled, derail, dhoora, dialer, diaper, diploe, dipole, dollar, dollop, doolie, dopier, eidola, elapid, ephori, hailed, hailer, hairdo, haired, halide, halloo, haloed, haloid, harped, herald, hilled, hiller, hilloa, hirple, holard, holder, holier, holler, holloa, hoodie, hoolie, hooped, hooper, hoopla, ladler, laired, loader, looped, looper, loreal, oorali, ordeal, oriole, oroide, paired, palier, palled, pallid, pallor, pardie, parled, parole, pedalo, pedlar, period, phalli, pillar, pilled, pleiad, polder, polled, poller, poodle, poohed, pooled, railed, redial, relaid, reload, repaid, repoll, rilled, roadeo, roadie, roiled, rolled.

 Words containing the letters "a-d-e-h-i-l-l-o-o-p-r"
 

+1 letter: haloperidols.

 

+2 letters: hyperboloidal.

 

+3 letters: orthopedically.

Source: compiled by the editor from various references; see credits.

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Alternative Orthography: Haloperidol


Hexadecimal (or equivalents, 770AD-1900s) (references)

48 61 6C 6F 70 65 72 69 64 6F 6C

Leonardo da Vinci (1452-1519; backwards) (references)

American Sign Language (origins from 1620-1817 in Italy and, especially, France) (references)

=

Semaphore (1791, in France) (references)

Braille (1829, in France) (references)

Morse Code (1836) (references)

....    .-    .-..    ---    .--.    .    .-.    ..    -..    ---    .-..

Dancing Men (Sir Arthur Conan Doyle, 1903) (references)

Binary Code (1918-1938, probably earlier) (references)

01001000 01100001 01101100 01101111 01110000 01100101 01110010 01101001 01100100 01101111 01101100

HTML Code (1990) (references)

&#72 &#97 &#108 &#111 &#112 &#101 &#114 &#105 &#100 &#111 &#108

ISO 10646 (1991-1993) (references)

0048 0061 006C 006F 0070 0065 0072 0069 0064 006F 006C

British Sign Language (Fingerspelling, BSL; 1992, British Deaf Association Dictionary of British Sign Language) (references)

Encryption (beginner's substitution cypher): (references)

4267788182718475708178

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INDEX

1. Definition
2. Synonyms
3. Crosswords
4. Quotations: Non-fiction
5. Usage Frequency
6. Expressions: Internet
7. Translations: Modern
8. Derivations
9. Anagrams
10. Orthography
11. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.