Glutathione Peroxidase

Definition: Glutathione Peroxidase

Glutathione Peroxidase

Noun

1. An enzyme in the body that is a powerful scavenger of free radicals.

Specialty Definition: Glutathione Peroxidase

Domain	Definition
Health	An enzyme catalyzing the oxidation of 2 moles of glutathione in the presence of hydrogen peroxide to yield oxidized glutathione and water. EC 1.11.1.9. (references)
Source: compiled by the editor from various references; see credits.

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Specialty Definition: Glutathione peroxidase

(From Wikipedia, the free Encyclopedia)

The enzyme glutathione peroxidase ( PDB 1GP1, EC 1.11.1.9) is found in the erythrocytes of mammals, and helps prevent peroxidation of cell membranes by consuming free peroxide in the cell. The summary reaction the enzyme catalyzes is:

2GSH + H₂O₂ → GSSG + 2H₂O

Where GSH represents reduced monomeric glutathione, and GSSG represents oxidized glutathione. Glutathione reductase then reduces the oxidized glutathione to complete the cycle:

GSSG + NADPH + H⁺ → 2 GSH + NADP⁺

Glutathione peroxidase is a tetramer, and the bovine erythrocyte enzyme has a molecular weight of 84,000. It is a selenium containing enzyme with 4 selenocysteine amino acid residues that participate in the actual mechanism of this enzyme.
Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Glutathione peroxidase."

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Crosswords: Glutathione Peroxidase

Specialty definitions using "glutathione peroxidase": Selenocysteine. (references)

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Non-Fiction Usage: Glutathione Peroxidase

Subject	Topic	Quote
Health		It is an essential component of glutathione peroxidase. (references)
Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Frequency of Internet Expressions: Glutathione Peroxidase

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.

Expression	Frequency per Day
antibody glutathione peroxidase	13
glutathione peroxidase	9
Source: compiled by the editor from various references; see credits.

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Anagrams: Glutathione Peroxidase

Scrabble® Enable2K-Verified Anagrams
	Words within the letters "a-a-d-e-e-e-g-h-i-i-l-n-o-o-p-r-s-t-t-u-x"
	-5 letters: radiotelephonies.
Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.

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