FACTOR XIIA

Domain	Definition
Health	Activated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation, kallikrein (with cofactor high molecular weight kininogen) cleaves factor XII to XIIa. Factor XIIa is then further cleaved by kallikrein, plasmin, and trypsin to yield smaller factor XII fragments (Hageman-Factor fragments). These fragments increase the activity of prekallikrein to kallikrein but decrease the procoagulant activity of factor XII. (references)
Source: compiled by the editor from various references; see credits.

Anagrams: FACTOR XIIA

Scrabble® Enable2K-Verified Anagrams
	Words within the letters "a-a-c-f-i-i-o-r-t-x"
	-4 letters: aortic, ataxic, factor, fracti, iatric, oxcart.
	-5 letters: acari, actor, afrit, aorta, atria, carat, coati, coria, craft, croft, facia, farci, fixit, ixora, ratio, riata, tafia, taroc, tiara, toric, torii, toxic, triac.
Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.