DYSTROPHIN

Domain	Definition
Health	A muscle protein localized in surface membranes which is the product of the Duchenne/Becker muscular dystrophy gene. Individuals with Duchenne muscular dystrophy usually lack dystrophin completely while those with Becker muscular dystrophy have dystrophin of an altered size. It shares features with other cytoskeletal proteins such as SPECTRIN and alpha-actinin but the precise function of dystrophin is not clear. One possible role might be to preserve the integrity and alignment of the plasma membrane to the myofibrils during muscle contraction and relaxation. MW 400 kDa. (references)
Source: compiled by the editor from various references; see credits.

Non-Fiction Usage: DYSTROPHIN

Subject	Topic	Quote
Health		One challenge the dystrophin gene presents is its enormous size. The gene is the largest gene yet identified in humans. (references)
		DMD results from an absence of the protein dystrophin, and BMD reflects a partly functional version of the same protein. (references)
		Some children with DMD (perhaps 15%) carry a mutation in the dystrophin gene that creates an erroneous DNA code signal to stop making the protein. (references)
Source: compiled by the editor from ICON Group International, Inc.; see credits.

Usage Frequency: DYSTROPHIN

"DYSTROPHIN" is generally used as a noun (singular) -- approximately 100.00% of the time. "DYSTROPHIN" is used about 37 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted)

Expressions: DYSTROPHIN

Frequency of Internet Keywords: DYSTROPHIN

Anagrams: DYSTROPHIN

Scrabble® Enable2K-Verified Anagrams
	Words within the letters "d-h-i-n-o-p-r-s-t-y"
	-1 letter: drypoints.
	-2 letters: drypoint, thyroids, thyrsoid, typhoids.
	-3 letters: disport, dronish, history, hornist, hydrops, hypnoid, phytoid, phytons, pythons, rhytons, syrphid, thyroid, torpids, tripods, tripody, tropins, trypsin, typhoid, typhons.
	-4 letters: dhotis, droits, dropsy, dryish, hydros, hyoids, intros, nitros, norths, orpins, phyton, pinots, pintos, piston, pitons, poinds, points, pointy, postin, prints, prions, prison, prosit, python, rhinos, rhyton, ripost.
	Words containing the letters "d-h-i-n-o-p-r-s-t-y"
	+4 letters: dryopithecines, hypermodernist.
	+5 letters: cyproheptadines, hypermodernists.
Source: compiled by the editor from various references; see credits. SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.

Alternative Orthography: DYSTROPHIN

Hexadecimal (or equivalents, 770AD-1900s) (references)

44 59 53 54 52 4F 50 48 49 4E

Leonardo da Vinci (1452-1519; backwards) (references)

American Sign Language (origins from 1620-1817 in Italy and, especially, France) (references)

⁼

Semaphore (1791, in France) (references)

Braille (1829, in France) (references)

Morse Code (1836) (references)

-.. -.--. ... - .-. --- .--. .... .. -.

Dancing Men (Sir Arthur Conan Doyle, 1903) (references)

Binary Code (1918-1938, probably earlier) (references)

01000100 01011001 01010011 01010100 01010010 01001111 01010000 01001000 01001001 01001110

HTML Code (1990) (references)

&#68 &#89 &#83 &#84 &#82 &#79 &#80 &#72 &#73 &#78

ISO 10646 (1991-1993) (references)

0044 0059 0053 0054 0052 004F 0050 0048 0049 004E

British Sign Language (Fingerspelling, BSL; 1992, British Deaf Association Dictionary of British Sign Language) (references)

Encryption (beginner's substitution cypher): (references)

Parts of Speech	Percent	Usage per 100 Million Words	Rank in English
Noun (singular)	100%	37	56,631

DYSTROPHIN

Specialty Definition: DYSTROPHIN

Health

Crosswords: DYSTROPHIN