Copyright © Philip M. Parker, INSEAD. Terms of Use.

CASPASES

"CASPASES" is a plural of: caspase.


Specialty Definition: CASPASES

DomainDefinition

Health

A family of intracellular cysteine endopeptidases. They play a key role in inflammation and mammalian apoptosis. They are specific for aspartic acid at the P1 position. They are divided into two classes based on the lengths of their N-terminal prodomains. Caspases-1,-2,-4,-5,-8, and -10 have long prodomains and -3,-6,-7,-9 have short prodomains. EC 3.4.22.-. (references)

Source: compiled by the editor from various references; see credits.

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Non-Fiction Usage: CASPASES

SubjectTopicQuote

Health

The McGill team hypothesizes that caspases may cause APP/beta-amyloid processing changes that sicken, but do not kill, neurons. (references)

But an excess amount of glutamate in the brain causes too much activity and brain cells quickly "burn out" from too much excitement, releasing more toxic chemicals, such as caspases, cytokines, monocytes, and oxygen-free radicals. (references)

In one series of studies, researchers at Columbia University College of Physicians and Surgeons sought to discover whether the activation of caspases could explain any of the features of AD's progression (Troy et al., 2000). They found that beta-amyloid induced one particular caspase not only to initiate the cell death pathway – to start apoptosis – but also to act as an effector of cell death, in essence becoming the "cell terminator. (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Frequency of Internet Keywords: CASPASES

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

activation apoptosis caspase caspases

3

caspases

2
Source: compiled by the editor from various references; see credits.

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Anagrams: CASPASES

Scrabble® Enable2K-Verified Anagrams

Words within the letters "a-a-c-e-p-s-s-s"

-2 letters: passes, scapes, spaces.

-3 letters: apace, apses, asses, capes, casas, cases, pacas, paces, pases, passe, scape, space, spaes, specs.

-4 letters: aces, apes, apse, asea, asps, cape, caps, casa, case, ceps, cess, paca, pace, pacs, pase, pass, peas, pecs, sacs, saps, sass, seas, secs, spae, spas, spec.

-5 letters: aas, ace, ape, asp, ass, cap, cep, ess.

 Words containing the letters "a-a-c-e-p-s-s-s"
 

+1 letter: seascapes.

 

+4 letters: backsplashes.

 

+5 letters: associateship, capablenesses, capaciousness, rapaciousness, sarcophaguses, scapegoatisms.

Source: compiled by the editor from various references; see credits.

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Alternative Orthography: CASPASES


Hexadecimal (or equivalents, 770AD-1900s) (references)

43 41 53 50 41 53 45 53

Leonardo da Vinci (1452-1519; backwards) (references)

American Sign Language (origins from 1620-1817 in Italy and, especially, France) (references)

=

Semaphore (1791, in France) (references)

Braille (1829, in France) (references)

Morse Code (1836) (references)

-.-.    .-    ...    .--.    .-    ...    .    ...

Dancing Men (Sir Arthur Conan Doyle, 1903) (references)

Binary Code (1918-1938, probably earlier) (references)

01000011 01000001 01010011 01010000 01000001 01010011 01000101 01010011

HTML Code (1990) (references)

&#67 &#65 &#83 &#80 &#65 &#83 &#69 &#83

ISO 10646 (1991-1993) (references)

0043 0041 0053 0050 0041 0053 0045 0053

British Sign Language (Fingerspelling, BSL; 1992, British Deaf Association Dictionary of British Sign Language) (references)

Encryption (beginner's substitution cypher): (references)

3735535035533953

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INDEX

1. Definition
2. Quotations: Non-fiction
3. Expressions: Internet
4. Anagrams
5. Orthography
6. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.