Copyright © Philip M. Parker, INSEAD. Terms of Use.

CALCINEURIN

Specialty Definition: CALCINEURIN

DomainDefinition

Health

A calcium- and calmodulin-binding protein present in highest concentrations in the central nervous system. Calcineurin is composed of two subunits. A catalytic subunit, calcineurin A, and a regulatory subunit, calcineurin B, with molecular weights of about 60 kD and 19 kD, respectively. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including histones, myosin light chain, and the regulatory subunit of cAMP-dependent protein kinase. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes in T-lymphocytes that act by inhibiting T-cell activation. EC 3.1.3.-. (references)

Source: compiled by the editor from various references; see credits.

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Usage Frequency: CALCINEURIN

"CALCINEURIN" is generally used as a noun (singular) -- approximately 100.00% of the time. "CALCINEURIN" is used about 10 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted)
Parts of SpeechPercentUsage per
100 Million Words
Rank in English
Noun (singular)100%10111,207

Source: compiled by the editor from several corpora; see credits.

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Frequency of Internet Keywords: CALCINEURIN

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

calcineurin inhibitor

17

calcineurin

11

calcineurin eczema inhibitor

6
Source: compiled by the editor from various references; see credits.

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Anagrams: CALCINEURIN

Scrabble® Enable2K-Verified Anagrams

Words within the letters "a-c-c-e-i-i-l-n-n-r-u"

-2 letters: unilinear.

-3 letters: caruncle, culicine, incliner, irenical.

-4 letters: aclinic, airline, aneurin, aniline, auricle, calcine, cannier, carline, cauline, cinerin, crucial, crucian, encinal, incline, lucarne, narcein, nuclear, nuclein, uncinal, unclean, unclear, unlearn.

-5 letters: accrue, acinic, aculei, aliner, anilin, annuli, anuric, cancel, cancer, canine, cannel, canner, cannie, carcel, carlin, carnie, celiac, cicale, cilice, circle, cleric, clinic, cuneal, cunner.

 Words containing the letters "a-c-c-e-i-i-l-n-n-r-u"
 

+4 letters: counterclaiming.

Source: compiled by the editor from various references; see credits.

SCRABBLE® is a registered trademark. All intellectual property rights in and to the game are owned in the U.S.A and Canada by Hasbro Inc., and throughout the rest of the world by J.W. Spear & Sons Limited of Maidenhead, Berkshire, England, a subsidiary of Mattel Inc. Mattel and Spear are not affiliated with Hasbro.

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Alternative Orthography: CALCINEURIN


Hexadecimal (or equivalents, 770AD-1900s) (references)

43 41 4C 43 49 4E 45 55 52 49 4E

Leonardo da Vinci (1452-1519; backwards) (references)

American Sign Language (origins from 1620-1817 in Italy and, especially, France) (references)

=

Semaphore (1791, in France) (references)

Braille (1829, in France) (references)

Morse Code (1836) (references)

-.-.    .-    .-..    -.-.    ..    -.    .    ..-    .-.    ..    -.

Dancing Men (Sir Arthur Conan Doyle, 1903) (references)

Binary Code (1918-1938, probably earlier) (references)

01000011 01000001 01001100 01000011 01001001 01001110 01000101 01010101 01010010 01001001 01001110

HTML Code (1990) (references)

&#67 &#65 &#76 &#67 &#73 &#78 &#69 &#85 &#82 &#73 &#78

ISO 10646 (1991-1993) (references)

0043 0041 004C 0043 0049 004E 0045 0055 0052 0049 004E

British Sign Language (Fingerspelling, BSL; 1992, British Deaf Association Dictionary of British Sign Language) (references)

Encryption (beginner's substitution cypher): (references)

3735463743483955524348

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INDEX

1. Usage Frequency
2. Expressions: Internet
3. Anagrams
4. Orthography
5. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.