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Cytokine

Definition: Cytokine

Cytokine

Noun

1. Any of various proteins secreted by cells of the immune system that serve to regulate the immune system.

Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved.
 


Specialty Definition: Cytokine

DomainDefinition

Medicine

Small but highly potent protein that modulates the activity of many cell types, including T and B cells. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Specialty Definition: Cytokine

(From Wikipedia, the free Encyclopedia)

Cytokines are small protein molecules that are the core of communication between immune system cells, and even between immune system cells and cells belonging to other tissue types. They are actively secreted by immune cells. Their action is often local, but sometimes can have global effects on the whole body.

There are a lot of known cytokines that have both stimulating and suppressing action on lymphocyte cells and immune response.

Cytokines act by binding to their cell-specific cytokine receptor. This receptor is located in the cell membrane and allows a signal cascade to start in the cell, that eventually will lead to biochemical and phenotypical changes in the target cell.

See also: Chemokines, Interleukines, Interferon

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Cytokine."

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Crosswords: Cytokine

English words defined with "cytokine": lymphokineTNF, tumor necrosis factor, tumour necrosis factor. (references)
Specialty definitions using "cytokine": aldesleukinfilgrastimInterferon-beta, Interleukin-11, Interleukin-12, Interleukin-13, Interleukin-14, Interleukin-15, Interleukin-16, Interleukin-17, Interleukin-18, Interleukin-8PEG-interferon alfa-2BReceptor, Ciliary Neurotrophic Factorsargramostim, SCH 54031, Sirolimus. (references)

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Commercial Usage: Cytokine

DomainTitle

Books

  • Cytokines and Cytokine Receptors: Physiology and Pathological Disorders (reference)

  • Homology Folding of Proteins: Application to Cytokine Engineering (reference)

  • Cytokine Regulation of Humoral Immunity: Basic and Clinical Aspects (reference)

  • Interleukin 12: Cellular and Molecular Immunology of an Important Regulatory Cytokine (Annals of the New York Academy of Sciences, V.795) (reference)

  • T-Cell Signaling of MacRophage Activation: Cell Contact-Dependent and Cytokine Signals (Molecular Biology Intelligence Unit) (reference)

    (more book examples)

Source: compiled by the editor from various references; see credits.

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Photo Album: Cytokine

ThumbnailDescription & Credit

Shown is a computer graphic of tgf-beta molecule. Tgf-beta belongs to a superfamily of fetal inducers and regressors, which signal specific patterns of cellular differentiation. Tgf-beta, a cytokine with three different isoforms, regulates many cellular functions including cell proliferation, differentiation, adhesion and migration. Four novel receptors were characterized that also act as serine/threonine kinases and one of these appears to be a tgf-beta receptor. Credit: Unknown photographer/artist.

Source: pictures compiled by the editor from various references; see picture credits.

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Non-Fiction Usage: Cytokine

SubjectTopicQuote

Health

Chemokines are small cytokine molecules that attract cells of the immune system. (references)

However, alternative explanations for the cytokine findings should not be ignored. (references)

After trauma, cytokine levels rise in the brain and spinal cord and at the site in the peripheral nervous system where the injury occurred. (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Usage Frequency: Cytokine

"Cytokine" is generally used as a noun (singular) -- approximately 94.74% of the time. "Cytokine" is used about 38 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted)
Parts of SpeechPercentUsage per
100 Million Words
Rank in English
Noun (singular)94.74%3657,479
Lexical Verb (infinitive)2.63%1339,140
Lexical Verb (base form)2.63%1339,140
                    Total100.00%38N/A

Source: compiled by the editor from several corpora; see credits.

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Expressions: Cytokine

Expression using "cytokine": Cytokine regulator. Additional references.

Hyphenated Usage

Beginning with "cytokine": cytokine-stimulation.

Source: compiled by the editor from various references; see credits.

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Frequency of Internet Keywords: Cytokine

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

cytokine

45

array cytokine

6

cocktail cytokine

4

cytokine intracellular staining

3

cytokine international society

2

cytokine interferon journal research

2

cytokine pharmasciences

2

cytokine definition

2

cytokine lipopolysaccharide mouse pcr rt

2
Source: compiled by the editor from various references; see credits.

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Modern Translation: Cytokine

Language Translations for "cytokine"; alternative meanings/domain in parentheses.

Dutch

  

cytokine. (various references)

   

French

  

cytokine. (various references)

   

German

  

Cytokin. (various references)

   

Greek 

  

κιτοκίνη, κυτοκίνη. (various references)

   

Italian

  

citochina. (various references)

   

Pig Latin

  

ytokinecay.(various references)

   

Spanish

  

citoquina. (various references)

Source: compiled by the editor from various translation references.

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Derivations & Misspellings: Cytokine

Derivations

Words beginning with "cytokine": cytokines, cytokineses, cytokinesis, cytokinetic. (additional references)


Misspellings

"Cytokine" is suggested in spellcheckers for the following: cimtidine, cystocele, cytidine, cytokin, cytokinin, ketomine. (additional references)

Source: compiled by the editor, based on several corpora (additional references).

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Anagrams: Cytokine

Scrabble® Enable2K-Verified Anagrams

Words within the letters "c-e-i-k-n-o-t-y"

-1 letter: kenotic, ketonic.

-2 letters: nicety, noetic, notice.

-3 letters: cento, coney, conky, conte, cyton, eikon, enoki, koine, ontic, token, toney, tonic, yince, yonic.

-4 letters: cent, cine, cion, cite, city, coin, coke, cone, coni, conk, cony, cote, etic, icky, icon, ikon, inky, into, keno, kent, keto, kine, kino, kite, knit, knot, kyte, neck, nice, nick, nite, nock.

 Words containing the letters "c-e-i-k-n-o-t-y"
 

+1 letter: cytokines.

 

+3 letters: cytokineses, cytokinesis, cytokinetic.

 

+4 letters: hydrokinetic, karyokinetic, skyrocketing.

 

+5 letters: psychokinetic.

Source: compiled by the editor from various references; see credits.

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INDEX

1. Definition
2. Crosswords
3. Usage: Commercial
4. Images: Photo Album
5. Quotations: Non-fiction
6. Usage Frequency
7. Expressions
8. Expressions: Internet
9. Translations: Modern
10. Derivations
11. Anagrams
12. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.