Copyright © Philip M. Parker, INSEAD. Terms of Use.
| Domain | Definition |
Health | The presence of antibodies directed against phospholipids (antibodies, antiphospholipid). The condition is associated with a variety of diseases, notably systemic lupus erythematosus and other connective tissue diseases, thrombopenia, and arterial or venous thromboses. In pregnancy it can cause abortion. Of the phospholipids, the cardiolipins show markedly elevated levels of anticardiolipin antibodies (antibodies, anticardiolipin). Present also are high levels of lupus anticoagulant (lupus coagulation inhibitor). (references) |
Source: compiled by the editor from various references; see credits. | |
(From Wikipedia, the free Encyclopedia)
It is an autoimmune disease, in which antibodies react against anionic phospholipids on ??? cell membranes. People with this disease also are thrombocytopenic (low platelet number).
It has an association with systemic lupus erythematosus (SLE), many people with antiphospholipid syndrome will go on to develop SLE. Being an autoimmune disease, it is more common in women than in men.
This disease is often picked up in women by noticing recurrent miscarriages, (usually terminating in the second trimester).
Antiphospholipid syndrome is tested for in the laboratory by two tests. The person will have a prolonged APTT, that will not be corrected with a 50:50 mixture with normal plasma. This result is known as lupus anticoagulant. As well this, there is an immunological test which detects if there are antibodies in the plasma that react with cardiolipin.
This disease is treated by giving aspirin to inhibit platelet activation, and warfarin as an anticoagulant (heparin is used during pregnancy, because of warfarin's teratogenicity.)
Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Antiphospholipid syndrome."
Crosswords: ANTIPHOSPHOLIPID SYNDROME |
| Specialty definitions using "ANTIPHOSPHOLIPID SYNDROME": Antibodies, Anticardiolipin, Antibodies, Antiphospholipid ♦ Lupus Coagulation Inhibitor. (references) |
| Domain | Title |
Books | |
Source: compiled by the editor from various references; see credits. | |
| The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com. |
| Expression | Frequency per Day |
antiphospholipid syndrome | 92 |
antibody antiphospholipid syndrome | 53 |
| Source: compiled by the editor from various references; see credits. | |
Hexadecimal (or equivalents, 770AD-1900s) (references)41 4E 54 49 50 48 4F 53 50 48 4F 4C 49 50 49 44 53 59 4E 44 52 4F 4D 45 |
| Leonardo da Vinci (1452-1519; backwards) (references)
|
Binary Code (1918-1938, probably earlier) (references)01000001 01001110 01010100 01001001 01010000 01001000 01001111 01010011 01010000 01001000 01001111 01001100 01001001 01010000 01001001 01000100 00100000 01010011 01011001 01001110 01000100 01010010 01001111 01001101 01000101 |
HTML Code (1990) (references)A N T I P H O S P H O L I P I D   S Y N D R O M E |
ISO 10646 (1991-1993) (references)0041 004E 0054 0049 0050 0048 004F 0053 0050 0048 004F 004C 0049 0050 0049 0044 0053 0059 004E 0044 0052 004F 004D 0045 |
Encryption (beginner's substitution cypher): (references)3548544350424953504249464350433825359483852494739 |
| 1. Crosswords 2. Usage: Commercial 3. Expressions: Internet 4. Orthography | 5. Bibliography |
Copyright © Philip M. Parker, INSEAD. Terms of Use.
