Copyright © Philip M. Parker, INSEAD. Terms of Use.

| Domain | Definition |
Health | A precursor to the amyloid-beta protein (beta/A4). Alterations in the expression of the amyloid beta-protein precursor (ABPP) gene, located on chromosome 21, plays a role in the development of the neuropathology common to both Alzheimer disease and Down syndrome. ABPP is associated with the extensive extracellular matrix secreted by neuronal cells. Upon cleavage, this precursor produces three proteins of varying amino acid lengths: 695, 751, and 770. The beta/A4 (695 amino acids) or beta-amyloid protein is the principal component of the extracellular amyloid in senile plaques found in Alzheimer disease, Down syndrome and, to a limited extent, in normal aging. (references) |
Source: compiled by the editor from various references; see credits. | |
Hexadecimal (or equivalents, 770AD-1900s) (references)41 4D 59 4C 4F 49 44      42 45 54 41 2D 50 52 4F 54 45 49 4E      50 52 45 43 55 52 53 4F 52 |
| Leonardo da Vinci (1452-1519; backwards) (references)
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Binary Code (1918-1938, probably earlier) (references)01000001 01001101 01011001 01001100 01001111 01001001 01000100 00100000 01000010 01000101 01010100 01000001 00101101 01010000 01010010 01001111 01010100 01000101 01001001 01001110 00100000 01010000 01010010 01000101 01000011 01010101 01010010 01010011 01001111 01010010 |
HTML Code (1990) (references)A M Y L O I D   B E T A - P R O T E I N   P R E C U R S O R |
ISO 10646 (1991-1993) (references)0041 004D 0059 004C 004F 0049 0044      0042 0045 0054 0041 002D 0050 0052 004F 0054 0045 0049 004E      0050 0052 0045 0043 0055 0052 0053 004F 0052 |
Encryption (beginner's substitution cypher): (references)3547594649433823639543515505249543943482505239375552534952 |
| 1. Orthography 2. Bibliography |
Copyright © Philip M. Parker, INSEAD. Terms of Use.