Copyright © Philip M. Parker, INSEAD. Terms of Use.
| Year | Description |
| 1993 | Invention patented by Heinrich Angenendt, Michael Meier, and Wolfram Schams on November 29th, 1993. Abstract: Process for preparing di(3-(2-chloroethylsulfonyl)-1-propyl)amine hydrochloride, by reacting 1 mol of an N,N-diallylcarboxamide of the formula (1) in which R is hydrogen, alkyl(C.sub.1 -C.sub.6) or cycloalkyl(C.sub.4 -C.sub.8) with about 4 to about 8 mol of mercaptoethanol at temperatures of about 0.degree. to about -70.degree. C. in the presence of pure oxygen or a mixture of oxygen with an inert gas or an inert gas mixture, if appropriate in an inert organic solvent, to give the carboxamide of the formula (2) in which R has the abovementioned meaning, hydrolyzing this compound with the aqueous solution of an alkaline agent at temperatures of about 40.degree. to about 120.degree. C. at a pH of about 10 to about 14, and reacting 1 mol of the di(3-(2-hydroxyethylthio)-1-propyl)amine thus obtained with about 4 to about 6 mol of chlorine gas in about 2 to about 15% hydrochloric acid at temperatures of about 20.degree. to about 110.degree. C. to give di(3-(2-chloroethylsulfonyl)-1-propyl)amine hydrochloride. |
| Source: selected by the editor from original sources. | |
Copyright © Philip M. Parker, INSEAD. Terms of Use.
