DNA and mRNA encoding an .alpha..sub.4 subunit of human neuronal nicotinic acetylcholine receptor and cells transformed with same

Year	Description
1995	Invention patented by Kathryn J. Elliott, Steven B. Ellis, and Michael M. Harpold on June 4th, 1995. Abstract: DNA encoding human neuronal nicotinic acetylcholine receptor alpha and beta subunits, mammalian and amphibian cells containing said DNA, methods for producing alpha and beta subunits and recombinant (i.e., isolated or substantially pure) alpha subunits (specifically .alpha..sub.4 and .alpha..sub.7) and beta subunits (specifically .beta..sub.4) are provided. In addition, combinations of subunits (i.e., .alpha..sub.1, .alpha..sub.2, .alpha..sub.3, .alpha..sub.4, and/or .alpha..sub.7 subunits in combination with .beta..sub.4 subunits; or .beta..sub.2, .beta..sub.3 and/or .beta..sub.4 subunits in combination with .alpha..sub.4 and/or .alpha..sub.7 subunits) are provided.
Source: selected by the editor from original sources.

Invention: DNA and mRNA encoding an .alpha..sub.4 subunit of human neuronal nicotinic acetylcholine receptor and cells transformed with same