DNA and RNA encoding proteins useful in the regulation of KB-containing genes, and cells containing same

  

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DNA and RNA encoding proteins useful in the regulation of KB-containing genes, and cells containing same

Invention: DNA and RNA encoding proteins useful in the regulation of KB-containing genes, and cells containing same

Year    Description
1993Invention patented by Gary J. Nabel, Roland M. Schmid, and Neil D. Perkins on December 16th, 1993. Abstract: Proteins, and corresponding DNA and RNA sequences, useful for the regulation of expression of .kappa.B-containing genes are disclosed. These proteins are useful to either stimulate or inhibit the expression of .kappa.B-containing genes. Proteins stimulating the expression of .kappa.B-containing genes have an amino acid sequence at least 80% identical to the amino acid sequence of from position 1 to position 374 of p100 [SEQ ID NO: 2]. Proteins having an inhibitory effect on the expression of .kappa.B-containing genes have sequences either at least 80% identical to the amino acid sequence of from position 407 to the carboxyl end of p100 [SEQ ID NO: 2] or having an amino acid sequence at least 80% identical to the amino sequence of either from position 1 to 100 sor from position 101 to position 374 of p100 [SEQ ID NO: 2].
Source: selected by the editor from original sources.

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