D-.beta.-lysylmethanediamine derivatives and preparation thereof

  

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D-.beta.-lysylmethanediamine derivatives and preparation thereof

Invention: D-.beta.-lysylmethanediamine derivatives and preparation thereof

Year    Description
1997Invention patented by Shinichi Kondo, Yoko Ikeda, Tomio Takeuchi, Rie Shinei, Shuichi Gomi, Seiji Shibahara, and Hiroo Hoshino on February 23th, 1997. Abstract: Now are provided (R)-3,6-diamino-N-(.omega.-aminoalkyl)-hexanamides which are novel compounds having the general formula (I): ##STR1## wherein n stands for 2-5, and which may be for example, (R)-3,6-diamino-N-(2-aminoethyl)hexanamide (n=2) and (R)-3,6-diamino-N-(3-aminopropyl)hexanamide (n=3). Their preparation process is also provided. These novel compounds and acid addition salts thereof have activities inhibitory against Gram-positive bacteria, Gram-negative bacteria and AIDS virus, as well as tumor cells and are chemically stable. These novel compounds and their salts are useful as chemotherapeutic agents for diseases caused by these bacteria or virus and also as antitumor agent.
Source: selected by the editor from original sources.

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