Cyclooxygenase

  

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Cyclooxygenase

Definition: Cyclooxygenase

Cyclooxygenase

Noun

1. Either of two related enzymes that control the production of prostaglandins and are blocked by aspirin.

Source: WordNet 1.7.1 Copyright © 2001 by Princeton University. All rights reserved.
 


Specialty Definition: Cyclooxygenase

DomainDefinition

Chemistry

Enzyme which is central to the production of prostaglandins at sites of inflammation. Source: European Union. (references)

Source: compiled by the editor from various references; see credits.

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Specialty Definition: Cyclooxygenase

(From Wikipedia, the free Encyclopedia)

Cyclooxygenase (COX) is a tissue enzyme that is responsible for tissue formation of important biological mediators called prostaglandins. Prostaglandins are involved in pain, inflammation and fever as well as cytoprotection in the stomach, hemostasis and blood flow in the kidneys. NSAIDS (non steroidal anti-inflammatory drugs) are used medicinally to block the cyclooxygenase and thus they act as pain killers, antipyretic drugs and for fighting some aspects of inflammatory reaction.

There are two isoenzymes, cyclooxygenase-1 and cyclooxygenase-2. Novel group of NSAIDs targets specifically cyclooxygenase-2 in this way avoiding a lot of side-effects that non-specific NSAIDS typically have.

Source: adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Cyclooxygenase."

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Synonym: Cyclooxygenase

Synonym: Cox (n). (additional references)

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Crosswords: Cyclooxygenase

Specialty definitions using "cyclooxygenase": BW-755CCyclooxygenase InhibitorsIloprostNordihydroguaiaretic AcidProstaglandin D2, ProstaglandinsThromboxanes. (references)

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Non-Fiction Usage: Cyclooxygenase

SubjectTopicQuote

Health

Many scientists think that when the inflammatory process begins in the brain, it sets off a vicious cycle that includes the activation of microglia, interleukins (IL), cyclooxygenase (COX), complement, cytokines, and amyloid deposition. (references)

Source: compiled by the editor from ICON Group International, Inc.; see credits.

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Usage Frequency: Cyclooxygenase

"Cyclooxygenase" is generally used as a noun (singular) -- approximately 100.00% of the time. "Cyclooxygenase" is used about 5 times out of a sample of 100 million words spoken or written in English. Its rank is based on over 700,000 words used in the English language. Some parts-of-speech are not covered due to the samples used by the British National Corpus. (note: percents less than one-hundredth of one percent have been omitted)
Parts of SpeechPercentUsage per
100 Million Words
Rank in English
Noun (singular)100%5157,705

Source: compiled by the editor from several corpora; see credits.

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Expressions: Cyclooxygenase

Expression using "cyclooxygenase": Cyclooxygenase Inhibitors. Additional references.

Hyphenated Usage

Beginning with "cyclooxygenase": cyclooxygenase-1, cyclooxygenase-2.

Source: compiled by the editor from various references; see credits.

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Frequency of Internet Keywords: Cyclooxygenase

The following statistics estimate the number of searches per day across the major English-language search engines as identified by various trade publications. Hyperlinks lead to commercial use of the expression at Amazon.com.
 
ExpressionFrequency
per Day

cyclooxygenase

10

1 cancer cyclooxygenase

5

2 celebrex coxibs cyclooxygenase vioxx

5

cancer cyclooxygenase expression

4

cyclooxygenase pathway

3
Source: compiled by the editor from various references; see credits.

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Modern Translation: Cyclooxygenase

Language Translations for "cyclooxygenase"; alternative meanings/domain in parentheses.

French

  

cyclo-oxygénase, COX. (various references)

   

Pig Latin

  

yclooxygenasecay

Source: compiled by the editor from various translation references.

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Anagrams: Cyclooxygenase

Scrabble® Enable2K-Verified Anagrams

Words within the letters "a-c-c-e-e-g-l-n-o-o-s-x-y-y"

-4 letters: synecology.

-5 letters: aglycones.

Source: compiled by the editor from various references; see credits.

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INDEX

1. Definition
2. Synonyms
3. Crosswords
4. Quotations: Non-fiction
5. Usage Frequency
6. Expressions
7. Expressions: Internet
8. Translations: Modern
9. Anagrams
10. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.