CXC chemokines as regulators of angiogenesis

  

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CXC chemokines as regulators of angiogenesis

Invention: CXC chemokines as regulators of angiogenesis

Year    Description
1995Invention patented by Robert M. Strieter, Peter J. Polverini, and Steven L. Kunkel on June 5th, 1995. Abstract: Disclosed are various discoveries concerning the angiogenic and angiostatic properties of the CXC chemokines, including the finding that the ELR motif controls the ability of these molecules to induce angiogenesis. Aspects of the invention include, for example, the identification of IP-10, MIG and certain IL-8 analogues as angiostatic agents, and their use in inhibiting angiogenesis in various systems.
Source: selected by the editor from original sources.

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