Anabaseine derivatives useful in the treatment of degenerative diseases of the nervous system

Invention: Anabaseine derivatives useful in the treatment of degenerative diseases of the nervous system

Year	Description
1996	Invention patented by William R. Kem, John A. Zoltewicz, Edwin M. Meyer, and Katalin Prokai-Tatrai on January 4th, 1996. Abstract: The invention concerns novel anabaseine-related compounds that are useful in treating certain degenerative neural diseases such as Alzheimer's and Parkinson's which apparently involve decreased function of cerebral cortical nicotinic receptors. The compounds showed activity in both in vitro and in active and passive active avoidance studies in animal models. An exemplary active compound is a 3-substituted 2,4-dimethoxy-benzylidene anabaseine.
Source: selected by the editor from original sources.