AT-2 antagonist inhibition of vascular restenosis

  

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AT-2 antagonist inhibition of vascular restenosis

Invention: AT-2 antagonist inhibition of vascular restenosis

Year    Description
1993Invention patented by Christopher F. Reilly, Stephen E. Delaszlo, Robert G. Johnson, and Tsuneo Fujita on July 18th, 1993. Abstract: Novel disubstituted 6-aminoquinazolinones of the Formula ##STR1## are useful as angiotensin-II receptor (subtype 2) antagonists (AT.sub.2 antagonists) alone or in combination with heparin, and can act to suppress the vascular stenosis which commonly occurs during the development of atherosclerosis and the restenosis following arterial angioplasty, stent placement, bypass surgery, heart transplantation or endarterectomy.
Source: selected by the editor from original sources.

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