APC mutation associated with familial colorectal cancer in Ashkenazi jews

Year	Description
1997	Invention patented by Steve Laken, Stephen Gruber, Gloria Petersen, Kenneth Kinzler, and Bert Vogelstein on January 30th, 1997. Abstract: During routine screening of a patient with a family history of colorectal cancer for truncating APC mutations, a novel missense mutation was identified. Upon further evaluation, it was found that 6% of Ashkenazi Jews carry this mutation, and that it was present in .sup..about. 20% of Ashkenazis with a family history of CRC. Probes, methods, and kits for identifying individuals affected with this missense mutation are provided.
Source: selected by the editor from original sources.

Invention: APC mutation associated with familial colorectal cancer in Ashkenazi jews