Copyright © Philip M. Parker, INSEAD. Terms of Use.

AMIDE HYDROLYSIS

Specialty Definition: Amide hydrolysis

(From Wikipedia, the free Encyclopedia)

Amide hydrolysis involves the C-N bond being broken in reaction with water (hydrolysis). The reaction is catalysed by either acid or alkali.

Procedure:

The amide is heated under reflux with moderately concentrated acqueous acid or alkali. If an acid is used, the product contains Ammonia ions. If a alkali is used, the carboxylic acid loses an H+ ion and the product contains carboxylate ions.

Source: the above text is adapted by the editor from Wikipedia, the free encyclopedia under a copyleft GNU Free Documentation License (GFDL) from the article "Amide hydrolysis."

Top     



  

Copyright © Philip M. Parker, INSEAD. Terms of Use.