ANTI-INFECTIVE AGENTS, QUINOLONE

  

Copyright © Philip M. Parker, INSEAD. Terms of Use.

ANTI-INFECTIVE AGENTS, QUINOLONE

Specialty Definition: ANTI-INFECTIVE AGENTS, QUINOLONE

DomainDefinition

Health

A group of synthetic antimicrobial agents which usually contain a 4-quinolinone ring structure. A few compounds belonging to this group have related nitrogen heterocyclic ring structures such as naphthyridine or phthalazine groups. All compounds in this group are substituted with an oxo group at the 4-position. The second-generation quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine moiety at the 6-position. The quinolones inhibit the A subunit of DNA gyrase and thus interfere with the ability of the enzyme to repair bacterial DNA breaks during replication. The compounds have a broad spectrum of activity against a variety of aerobic bacteria. (references)

Source: compiled by the editor from various references; see credits.

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Alternative Orthography: ANTI-INFECTIVE AGENTS, QUINOLONE


Hexadecimal (or equivalents, 770AD-1900s) (references)

41 4E 54 49 2D 49 4E 46 45 43 54 49 56 45      41 47 45 4E 54 53 2C      51 55 49 4E 4F 4C 4F 4E 45

Leonardo da Vinci (1452-1519; backwards) (references)

        

Binary Code (1918-1938, probably earlier) (references)

01000001 01001110 01010100 01001001 00101101 01001001 01001110 01000110 01000101 01000011 01010100 01001001 01010110 01000101 00100000 01000001 01000111 01000101 01001110 01010100 01010011 00101100 00100000 01010001 01010101 01001001 01001110 01001111 01001100 01001111 01001110 01000101

HTML Code (1990) (references)

&#65 &#78 &#84 &#73 &#45 &#73 &#78 &#70 &#69 &#67 &#84 &#73 &#86 &#69 &#32 &#65 &#71 &#69 &#78 &#84 &#83 &#44 &#32 &#81 &#85 &#73 &#78 &#79 &#76 &#79 &#78 &#69

ISO 10646 (1991-1993) (references)

0041 004E 0054 0049 002D 0049 004E 0046 0045 0043 0054 0049 0056 0045      0041 0047 0045 004E 0054 0053 002C      0051 0055 0049 004E 004F 004C 004F 004E 0045

Encryption (beginner's substitution cypher): (references)

35485443154348403937544356392354139485453142515543484946494839

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INDEX

1. Orthography
2. Bibliography


  

Copyright © Philip M. Parker, INSEAD. Terms of Use.